CDK11B
Entrez ID: 984
Full name: cyclin dependent kinase 11B
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CMGC: CDK: CDK11
Chromosomal location: 1p36.33
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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CDK11B
Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression....
Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.
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GO - Biological processes (BP):
apoptotic process, mitotic cell cycle, protein phosphorylation, regulation of cell growth, regulation of gene expression, regulation of mitotic cell cycle, regulation of mRNA processing, regulation of transcription, DNA-templated...
apoptotic process, mitotic cell cycle, protein phosphorylation, regulation of cell growth, regulation of gene expression, regulation of mitotic cell cycle, regulation of mRNA processing, regulation of transcription, DNA-templated
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GO - Molecular function (MF):
ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity, RNA binding...
ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity, RNA binding
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GO - Cellular component (CC):
nucleus, cytoplasm...
nucleus, cytoplasm
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cyclin dependent kinase 11B
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Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
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Minimum 10 samples
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Kaplan plot for CDK11B in
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*NOTE: the Kaplan plots were collected from OncoLnc