GTF2F1
Entrez ID: 2962
Full name: general transcription factor IIF subunit 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Atypical: GTF2F1
Chromosomal location: 19p13.3
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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GTF2F1
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation....
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
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GO - Biological processes (BP):
7-methylguanosine mRNA capping, fibroblast growth factor receptor signaling pathway, mRNA splicing, via spliceosome, negative regulation of protein binding, positive regulation of transcription by RNA polymerase II, positive regulation of transcription elongation from RNA polymerase II promoter, pos...
7-methylguanosine mRNA capping, fibroblast growth factor receptor signaling pathway, mRNA splicing, via spliceosome, negative regulation of protein binding, positive regulation of transcription by RNA polymerase II, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of viral transcription, response to virus, RNA metabolic process, snRNA transcription by RNA polymerase II, transcription by RNA polymerase II, transcription elongation from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter
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GO - Molecular function (MF):
DNA binding, phosphatase activator activity, promoter-specific chromatin binding, protein domain specific binding, protein phosphatase binding, RNA binding, RNA polymerase II general transcription initiation factor activity, transcription coactivator activity, transcription factor binding...
DNA binding, phosphatase activator activity, promoter-specific chromatin binding, protein domain specific binding, protein phosphatase binding, RNA binding, RNA polymerase II general transcription initiation factor activity, transcription coactivator activity, transcription factor binding
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GO - Cellular component (CC):
nucleoplasm, nucleus, transcription factor TFIID complex, transcription factor TFIIF complex, cell junction, intracellular membrane-bounded organelle, protein-containing complex...
nucleoplasm, nucleus, transcription factor TFIID complex, transcription factor TFIIF complex, cell junction, intracellular membrane-bounded organelle, protein-containing complex
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general transcription factor IIF subunit 1
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Gatekeeper
A-loop
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αC-helix
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A-loop
G-loop
αC-helix
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Kaplan plot for GTF2F1 in
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*NOTE: the Kaplan plots were collected from OncoLnc