TIE1
Entrez ID: 7075
Full name: tyrosine kinase with immunoglobulin like and EGF like domains 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: TK: Tie
Chromosomal location: 1p34.2
Substructure location: Gatekeeper: 917 A-loop: 996...1018 G-loop: [N/A] αC-helix: [N/A]
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TIE1
Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis....
Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
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GO - Biological processes (BP):
angiogenesis, in utero embryonic development, mesoderm development, multicellular organism development, negative regulation of angiogenesis, negative regulation of cell migration, plasma membrane fusion, positive regulation of angiogenesis, positive regulation of kinase activity, response to retinoi...
angiogenesis, in utero embryonic development, mesoderm development, multicellular organism development, negative regulation of angiogenesis, negative regulation of cell migration, plasma membrane fusion, positive regulation of angiogenesis, positive regulation of kinase activity, response to retinoic acid, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway, vasculogenesis
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GO - Molecular function (MF):
ATP binding, transmembrane receptor protein tyrosine kinase activity...
ATP binding, transmembrane receptor protein tyrosine kinase activity
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GO - Cellular component (CC):
integral component of plasma membrane, receptor complex...
integral component of plasma membrane, receptor complex
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tyrosine kinase with immunoglobulin like and EGF like domains 1
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Kaplan plot for TIE1 in
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*NOTE: the Kaplan plots were collected from OncoLnc