GUCY2F
Entrez ID: 2986
Full name: guanylate cyclase 2F, retinal
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: RGC: RGC
Chromosomal location: Xq22.3-q23
Substructure location: Gatekeeper: 623 A-loop: [N/A] G-loop: [N/A] αC-helix: [N/A]
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GUCY2F
Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors (PubMed:7777544). Plays an essential role in phototransduction, by mediating cGMP replenishment (By similarity). May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer se...
Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors (PubMed:7777544). Plays an essential role in phototransduction, by mediating cGMP replenishment (By similarity). May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity).
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GO - Biological processes (BP):
cGMP biosynthetic process, cGMP-mediated signaling, detection of light stimulus involved in visual perception, receptor guanylyl cyclase signaling pathway, regulation of rhodopsin mediated signaling pathway, signal transduction, visual perception...
cGMP biosynthetic process, cGMP-mediated signaling, detection of light stimulus involved in visual perception, receptor guanylyl cyclase signaling pathway, regulation of rhodopsin mediated signaling pathway, signal transduction, visual perception
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GO - Molecular function (MF):
ATP binding, GTP binding, guanylate cyclase activity, identical protein binding, natriuretic peptide receptor activity, peptide hormone binding, peptide receptor activity, protein-containing complex binding, protein kinase activity, signaling receptor activity...
ATP binding, GTP binding, guanylate cyclase activity, identical protein binding, natriuretic peptide receptor activity, peptide hormone binding, peptide receptor activity, protein-containing complex binding, protein kinase activity, signaling receptor activity
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GO - Cellular component (CC):
nuclear outer membrane, integral component of plasma membrane, plasma membrane, photoreceptor disc membrane, rod photoreceptor outer segment...
nuclear outer membrane, integral component of plasma membrane, plasma membrane, photoreceptor disc membrane, rod photoreceptor outer segment
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guanylate cyclase 2F, retinal
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*NOTE: the Kaplan plots were collected from OncoLnc