NME5
Entrez ID: 8382
Full name: NME/NM23 family member 5
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: NDK
Chromosomal location: 5q31.2
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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NME5
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity)...
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).
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GO - Biological processes (BP):
cilium assembly, CTP biosynthetic process, epithelial cilium movement involved in extracellular fluid movement, GTP biosynthetic process, negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway, nucleoside metabolic process, spermatid development, spermatogenesis, UTP b...
cilium assembly, CTP biosynthetic process, epithelial cilium movement involved in extracellular fluid movement, GTP biosynthetic process, negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway, nucleoside metabolic process, spermatid development, spermatogenesis, UTP biosynthetic process, ventricular system development
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GO - Molecular function (MF):
nucleoside diphosphate kinase activity...
nucleoside diphosphate kinase activity
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GO - Cellular component (CC):
extracellular region, sperm flagellum...
extracellular region, sperm flagellum
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NME/NM23 family member 5
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Kaplan plot for NME5 in
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*NOTE: the Kaplan plots were collected from OncoLnc