PTK7
Entrez ID: 5754
Full name: protein tyrosine kinase 7 (inactive)
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: TK: CCK4
Chromosomal location: 6p21.1
Substructure location: Gatekeeper: 888 A-loop: [N/A] G-loop: [N/A] αC-helix: [N/A]
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PTK7
Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization ...
Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
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GO - Biological processes (BP):
actin cytoskeleton reorganization, axis elongation, cell adhesion, cell migration, cellular response to retinoic acid, cochlea morphogenesis, convergent extension, coronary vasculature development, establishment of epithelial cell apical/basal polarity, establishment of planar polarity, lung-associa...
actin cytoskeleton reorganization, axis elongation, cell adhesion, cell migration, cellular response to retinoic acid, cochlea morphogenesis, convergent extension, coronary vasculature development, establishment of epithelial cell apical/basal polarity, establishment of planar polarity, lung-associated mesenchyme development, planar cell polarity pathway involved in neural tube closure, positive regulation of canonical Wnt signaling pathway, positive regulation of neuron projection development, signal transduction, ventricular septum development, wound healing
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GO - Molecular function (MF):
ATP binding, coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway, protein kinase activity...
ATP binding, coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway, protein kinase activity
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GO - Cellular component (CC):
integral component of plasma membrane, cell-cell junction, focal adhesion...
integral component of plasma membrane, cell-cell junction, focal adhesion
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protein tyrosine kinase 7 (inactive)
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Kaplan plot for PTK7 in
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*NOTE: the Kaplan plots were collected from OncoLnc