FASTK
Entrez ID: 10922
Full name: Fas activated serine/threonine kinase
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Atypical: FAST
Chromosomal location: 7q36.1
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
Please click HERE
for better display.
FASTK
Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor....
Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor.
View more >>
GO - Biological processes (BP):
apoptotic signaling pathway, protein phosphorylation, regulation of RNA splicing...
apoptotic signaling pathway, protein phosphorylation, regulation of RNA splicing
View more >>
GO - Molecular function (MF):
ATP binding, Fas-activated serine/threonine kinase activity, protein serine/threonine kinase activity, RNA binding...
ATP binding, Fas-activated serine/threonine kinase activity, protein serine/threonine kinase activity, RNA binding
View more >>
GO - Cellular component (CC):
mitochondrial matrix...
mitochondrial matrix
View more >>
Fas activated serine/threonine kinase
Control panel
Show dataset:
Show substructure:
All sites
Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
Filter mutation sites
All sites
Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
Data table is loading....
Kaplan plot for FASTK in
Download patient group data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from OncoLnc