TESK1
Entrez ID: 7016
Full name: testis associated actin remodelling kinase 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: TKL: LISK: TESK
Chromosomal location: 9p13.3
Substructure location: Gatekeeper: 129 A-loop: 195...205, 209...222 G-loop: [N/A] αC-helix: [N/A]
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TESK1
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Probably plays a central role at and after the meiotic phase of spermatogenesis (By similarity)....
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Probably plays a central role at and after the meiotic phase of spermatogenesis (By similarity).
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GO - Biological processes (BP):
actin cytoskeleton organization, negative regulation of protein autophosphorylation, negative regulation of protein serine/threonine kinase activity, positive regulation of stress fiber assembly, regulation of protein localization, spermatogenesis...
actin cytoskeleton organization, negative regulation of protein autophosphorylation, negative regulation of protein serine/threonine kinase activity, positive regulation of stress fiber assembly, regulation of protein localization, spermatogenesis
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GO - Molecular function (MF):
ATP binding, metal ion binding, protein C-terminus binding, protein kinase binding, protein serine/threonine/tyrosine kinase activity, protein serine/threonine kinase activity, protein tyrosine kinase activity...
ATP binding, metal ion binding, protein C-terminus binding, protein kinase binding, protein serine/threonine/tyrosine kinase activity, protein serine/threonine kinase activity, protein tyrosine kinase activity
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GO - Cellular component (CC):
cytosol, nucleus, cytoplasm, cytoplasmic vesicle...
cytosol, nucleus, cytoplasm, cytoplasmic vesicle
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testis associated actin remodelling kinase 1
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Kaplan plot for TESK1 in
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*NOTE: the Kaplan plots were collected from OncoLnc