AMHR2
Entrez ID: 269
Full name: anti-Mullerian hormone receptor type 2
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: TKL: STKR: STKR2
Chromosomal location: 12q13.13
Substructure location: Gatekeeper: 279 A-loop: 350...360, 373...385 G-loop: [N/A] αC-helix: [N/A]
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AMHR2
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hor...
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
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GO - Biological processes (BP):
anti-Mullerian hormone signaling pathway, blood vessel development, BMP signaling pathway, cellular response to growth factor stimulus, female gonad development, male gonad development, Mullerian duct regression, protein phosphorylation, sex differentiation, transforming growth factor beta receptor ...
anti-Mullerian hormone signaling pathway, blood vessel development, BMP signaling pathway, cellular response to growth factor stimulus, female gonad development, male gonad development, Mullerian duct regression, protein phosphorylation, sex differentiation, transforming growth factor beta receptor signaling pathway, vasculature development
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GO - Molecular function (MF):
anti-Mullerian hormone receptor activity, ATP binding, hormone binding, metal ion binding, protein serine/threonine kinase activity, transforming growth factor beta-activated receptor activity, transforming growth factor beta receptor activity, type II...
anti-Mullerian hormone receptor activity, ATP binding, hormone binding, metal ion binding, protein serine/threonine kinase activity, transforming growth factor beta-activated receptor activity, transforming growth factor beta receptor activity, type II
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GO - Cellular component (CC):
integral component of plasma membrane, plasma membrane, receptor complex...
integral component of plasma membrane, plasma membrane, receptor complex
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anti-Mullerian hormone receptor type 2
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Kaplan plot for AMHR2 in
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*NOTE: the Kaplan plots were collected from OncoLnc