LRRK1
Entrez ID: 79705
Full name: leucine rich repeat kinase 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: TKL: LRRK
Chromosomal location: 15q26.3
Substructure location: Gatekeeper: 1334 A-loop: 1408...1429 G-loop: [N/A] αC-helix: [N/A]
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LRRK1
NA...
NA
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GO - Biological processes (BP):
bone resorption, negative regulation of peptidyl-tyrosine phosphorylation, osteoclast development, positive regulation of canonical Wnt signaling pathway, positive regulation of intracellular signal transduction, positive regulation of peptidyl-tyrosine phosphorylation...
bone resorption, negative regulation of peptidyl-tyrosine phosphorylation, osteoclast development, positive regulation of canonical Wnt signaling pathway, positive regulation of intracellular signal transduction, positive regulation of peptidyl-tyrosine phosphorylation
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GO - Molecular function (MF):
ATP binding, GTP binding, identical protein binding, metal ion binding, protein serine/threonine kinase activity...
ATP binding, GTP binding, identical protein binding, metal ion binding, protein serine/threonine kinase activity
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GO - Cellular component (CC):
cytosol, mitochondrion...
cytosol, mitochondrion
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leucine rich repeat kinase 1
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A-loop
G-loop
αC-helix
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G-loop
αC-helix
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Minimum 5 samples
Minimum 10 samples
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Kaplan plot for LRRK1 in
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*NOTE: the Kaplan plots were collected from OncoLnc