MAP3K21
Entrez ID: 84451
Full name: mitogen-activated protein kinase kinase kinase 21
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: TKL: MLK: MLK
Chromosomal location: 1q42.2
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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MAP3K21
Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways....
Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.
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GO - Biological processes (BP):
activation of JUN kinase activity, protein autophosphorylation, protein phosphorylation...
activation of JUN kinase activity, protein autophosphorylation, protein phosphorylation
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GO - Molecular function (MF):
ATP binding, MAP kinase kinase kinase activity, protein homodimerization activity...
ATP binding, MAP kinase kinase kinase activity, protein homodimerization activity
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GO - Cellular component (CC):
-...
-
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mitogen-activated protein kinase kinase kinase 21
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Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
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Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
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Kaplan plot for MAP3K21 in
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*NOTE: the Kaplan plots were collected from OncoLnc