PEAK3
Entrez ID: 374872
Full name: PEAK family member 3
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: PEAK
Chromosomal location: 19p13.3
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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PEAK3
Probable catalytically inactive kinase (Probable). Interacts with CRK-II and antagonizes CRK-II-signaling. Prevents the formation of CRK-II-dependent membrane ruffling and lamellipodia-like extensions (PubMed:31311869)....
Probable catalytically inactive kinase (Probable). Interacts with CRK-II and antagonizes CRK-II-signaling. Prevents the formation of CRK-II-dependent membrane ruffling and lamellipodia-like extensions (PubMed:31311869).
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GO - Biological processes (BP):
protein phosphorylation, regulation of actin cytoskeleton organization, regulation of cell shape...
protein phosphorylation, regulation of actin cytoskeleton organization, regulation of cell shape
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GO - Molecular function (MF):
protein kinase activity, protein self-association...
protein kinase activity, protein self-association
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GO - Cellular component (CC):
actin cytoskeleton, focal adhesion...
actin cytoskeleton, focal adhesion
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PEAK family member 3
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αC-helix
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A-loop
G-loop
αC-helix
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Kaplan plot for PEAK3 in
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*NOTE: the Kaplan plots were collected from OncoLnc