PXK
Entrez ID: 54899
Full name: PX domain containing serine/threonine kinase like
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: Slob
Chromosomal location: 3p14.3
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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PXK
Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity....
Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.
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GO - Biological processes (BP):
inflammatory response, modulation of chemical synaptic transmission, negative regulation of ATPase activity, negative regulation of ion transport, protein phosphorylation, regulation of membrane potential...
inflammatory response, modulation of chemical synaptic transmission, negative regulation of ATPase activity, negative regulation of ion transport, protein phosphorylation, regulation of membrane potential
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GO - Molecular function (MF):
actin binding, phosphatidylinositol binding, protein C-terminus binding...
actin binding, phosphatidylinositol binding, protein C-terminus binding
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GO - Cellular component (CC):
centriolar satellite, cytosol, nucleus, plasma membrane, cytoplasm, protein-containing complex...
centriolar satellite, cytosol, nucleus, plasma membrane, cytoplasm, protein-containing complex
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PX domain containing serine/threonine kinase like
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A-loop
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αC-helix
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A-loop
G-loop
αC-helix
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Minimum 5 samples
Minimum 10 samples
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Kaplan plot for PXK in
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*NOTE: the Kaplan plots were collected from OncoLnc