ADCK1
Entrez ID: 57143
Full name: aarF domain containing kinase 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Atypical: ABC1: ABC1-B
Chromosomal location: 14q24.3
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
Please click HERE
for better display.
ADCK1
Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase-independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT (PubMed:31125351). The action of this enzyme is not yet clear (Probable). It is...
Appears to be essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 in a kinase-independent manner to regulate essential mitochondrial structural proteins OPA1 and IMMT (PubMed:31125351). The action of this enzyme is not yet clear (Probable). It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable).
View more >>
GO - Biological processes (BP):
negative regulation of mitochondrial fusion, positive regulation of cristae formation...
negative regulation of mitochondrial fusion, positive regulation of cristae formation
View more >>
GO - Molecular function (MF):
ATP binding, protein serine/threonine kinase activity...
ATP binding, protein serine/threonine kinase activity
View more >>
GO - Cellular component (CC):
extracellular region...
extracellular region
View more >>
aarF domain containing kinase 1
Control panel
Show dataset:
Show substructure:
All sites
Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
Filter mutation sites
All sites
Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
Data table is loading....
Kaplan plot for ADCK1 in
Download patient group data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from OncoLnc