MAP4K3
Entrez ID: 8491
Full name: mitogen-activated protein kinase kinase kinase kinase 3
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: STE: STE20: KHS
Chromosomal location: 2p22.1
Substructure location: Gatekeeper: 90 A-loop: 153...164, 167...176 G-loop: 22...28 αC-helix: 56...66
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MAP4K3
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway....
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
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GO - Biological processes (BP):
activation of protein kinase activity, intracellular signal transduction, JNK cascade, MAPK cascade, protein phosphorylation, regulation of mitotic cell cycle, response to tumor necrosis factor, response to UV, signal transduction by protein phosphorylation, stress-activated protein kinase signaling...
activation of protein kinase activity, intracellular signal transduction, JNK cascade, MAPK cascade, protein phosphorylation, regulation of mitotic cell cycle, response to tumor necrosis factor, response to UV, signal transduction by protein phosphorylation, stress-activated protein kinase signaling cascade
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GO - Molecular function (MF):
ATP binding, MAP kinase kinase kinase kinase activity, protein kinase activity, protein serine/threonine kinase activity...
ATP binding, MAP kinase kinase kinase kinase activity, protein kinase activity, protein serine/threonine kinase activity
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GO - Cellular component (CC):
cytoplasm...
cytoplasm
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mitogen-activated protein kinase kinase kinase kinase 3
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Kaplan plot for MAP4K3 in
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*NOTE: the Kaplan plots were collected from OncoLnc