NME8
Entrez ID: 51314
Full name: NME/NM23 family member 8
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: NDK
Chromosomal location: 7p14.1
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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NME8
Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor re...
Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds.
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GO - Biological processes (BP):
cell differentiation, cell redox homeostasis, cellular response to reactive oxygen species, cilium assembly, flagellated sperm motility, multicellular organism development, spermatogenesis...
cell differentiation, cell redox homeostasis, cellular response to reactive oxygen species, cilium assembly, flagellated sperm motility, multicellular organism development, spermatogenesis
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GO - Molecular function (MF):
microtubule binding...
microtubule binding
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GO - Cellular component (CC):
outer dynein arm, cell, sperm cytoplasmic droplet, sperm principal piece...
outer dynein arm, cell, sperm cytoplasmic droplet, sperm principal piece
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NME/NM23 family member 8
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Kaplan plot for NME8 in
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*NOTE: the Kaplan plots were collected from OncoLnc