CAMKK1
Entrez ID: 84254
Full name: calcium/calmodulin dependent protein kinase kinase 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: CAMKK: CAMKK-Meta
Chromosomal location: 17p13.2
Substructure location: Gatekeeper: 230 A-loop: 292...315 G-loop: [N/A] αC-helix: [N/A]
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CAMKK1
Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibi...
Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.
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GO - Biological processes (BP):
intracellular signal transduction, positive regulation of protein kinase activity...
intracellular signal transduction, positive regulation of protein kinase activity
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GO - Molecular function (MF):
ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein serine/threonine kinase activity...
ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein serine/threonine kinase activity
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GO - Cellular component (CC):
cytosol, nucleoplasm, cytoplasm...
cytosol, nucleoplasm, cytoplasm
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calcium/calmodulin dependent protein kinase kinase 1
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*NOTE: the Kaplan plots were collected from OncoLnc