HIPK4
Entrez ID: 147746
Full name: homeodomain interacting protein kinase 4
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CMGC: DYRK: HIPK
Chromosomal location: 19q13.2
Substructure location: Gatekeeper: 89 A-loop: [N/A] G-loop: [N/A] αC-helix: [N/A]
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HIPK4
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors (Potential)....
Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors (Potential).
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GO - Biological processes (BP):
histone phosphorylation, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, protein autophosphorylation, regulation of signal transduction by p53 class mediator...
histone phosphorylation, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, protein autophosphorylation, regulation of signal transduction by p53 class mediator
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GO - Molecular function (MF):
ATP binding, protein serine/threonine kinase activity, protein tyrosine kinase activity...
ATP binding, protein serine/threonine kinase activity, protein tyrosine kinase activity
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GO - Cellular component (CC):
nucleus, cytoplasm...
nucleus, cytoplasm
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homeodomain interacting protein kinase 4
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Kaplan plot for HIPK4 in
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*NOTE: the Kaplan plots were collected from OncoLnc