UHMK1
Entrez ID: 127933
Full name: U2AF homology motif kinase 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: KIS
Chromosomal location: 1q23.3
Substructure location: Gatekeeper: 111 A-loop: 176...196 G-loop: [N/A] αC-helix: [N/A]
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UHMK1
Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity)....
Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity).
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GO - Biological processes (BP):
cell cycle arrest, neuron projection development, peptidyl-serine phosphorylation, positive regulation of translational initiation, protein autophosphorylation, regulation of protein export from nucleus...
cell cycle arrest, neuron projection development, peptidyl-serine phosphorylation, positive regulation of translational initiation, protein autophosphorylation, regulation of protein export from nucleus
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GO - Molecular function (MF):
ATP binding, protein serine/threonine kinase activity, ribonucleoprotein complex binding, RNA binding, transferase activity...
ATP binding, protein serine/threonine kinase activity, ribonucleoprotein complex binding, RNA binding, transferase activity
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GO - Cellular component (CC):
Golgi apparatus, nucleoplasm, nucleus, axon, cytoplasm, dendrite cytoplasm, midbody, neuronal ribonucleoprotein granule...
Golgi apparatus, nucleoplasm, nucleus, axon, cytoplasm, dendrite cytoplasm, midbody, neuronal ribonucleoprotein granule
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U2AF homology motif kinase 1
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A-loop
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αC-helix
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αC-helix
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Minimum 10 samples
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Kaplan plot for UHMK1 in
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*NOTE: the Kaplan plots were collected from OncoLnc