TBCK
Entrez ID: 93627
Full name: TBC1 domain containing kinase
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: TBCK
Chromosomal location: 4q24
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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TBCK
Involved in the modulation of mTOR signaling and expression of mTOR complex components (PubMed:27040691, PubMed:23977024). Involved in the regulation of cell proliferation and growth (PubMed:23977024, PubMed:24576458). Involved in the control of actin-cytoskeleton organization (PubMed:23977024)....
Involved in the modulation of mTOR signaling and expression of mTOR complex components (PubMed:27040691, PubMed:23977024). Involved in the regulation of cell proliferation and growth (PubMed:23977024, PubMed:24576458). Involved in the control of actin-cytoskeleton organization (PubMed:23977024).
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GO - Biological processes (BP):
actin cytoskeleton organization, activation of GTPase activity, cell population proliferation, intracellular protein transport, regulation of TOR signaling...
actin cytoskeleton organization, activation of GTPase activity, cell population proliferation, intracellular protein transport, regulation of TOR signaling
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GO - Molecular function (MF):
ATP binding, GTPase activator activity, protein kinase activity, Rab GTPase binding...
ATP binding, GTPase activator activity, protein kinase activity, Rab GTPase binding
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GO - Cellular component (CC):
mitotic spindle, cytoplasm, midbody...
mitotic spindle, cytoplasm, midbody
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TBC1 domain containing kinase
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Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
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Minimum 10 samples
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Kaplan plot for TBCK in
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*NOTE: the Kaplan plots were collected from OncoLnc