MYO3B
Entrez ID: 140469
Full name: myosin IIIB
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: STE: STE20: NinaC
Chromosomal location: 2q31.1
Substructure location: Gatekeeper: 106 A-loop: 173...196 G-loop: [N/A] αC-helix: [N/A]
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MYO3B
Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of micr...
Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments.
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GO - Biological processes (BP):
cochlea morphogenesis, response to stimulus, sensory perception of sound, visual perception...
cochlea morphogenesis, response to stimulus, sensory perception of sound, visual perception
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GO - Molecular function (MF):
actin binding, ATP binding, motor activity, protein serine/threonine kinase activity...
actin binding, ATP binding, motor activity, protein serine/threonine kinase activity
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GO - Cellular component (CC):
myosin complex, cytoplasm, stereocilium tip...
myosin complex, cytoplasm, stereocilium tip
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myosin IIIB
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Kaplan plot for MYO3B in
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*NOTE: the Kaplan plots were collected from OncoLnc