TRIB2
Entrez ID: 28951
Full name: tribbles pseudokinase 2
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CAMK: Trbl
Chromosomal location: 2p24.3
Substructure location: Gatekeeper: 130 A-loop: [N/A] G-loop: [N/A] αC-helix: [N/A]
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TRIB2
Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity)....
Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity).
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GO - Biological processes (BP):
negative regulation of fat cell differentiation, negative regulation of interleukin-10 biosynthetic process, negative regulation of protein kinase activity, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein phosphorylation, regulation of MAP kinase activity...
negative regulation of fat cell differentiation, negative regulation of interleukin-10 biosynthetic process, negative regulation of protein kinase activity, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein phosphorylation, regulation of MAP kinase activity
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GO - Molecular function (MF):
mitogen-activated protein kinase kinase binding, protein kinase inhibitor activity, transcription factor binding, ubiquitin protein ligase binding, ubiquitin-protein transferase regulator activity...
mitogen-activated protein kinase kinase binding, protein kinase inhibitor activity, transcription factor binding, ubiquitin protein ligase binding, ubiquitin-protein transferase regulator activity
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GO - Cellular component (CC):
cytoskeleton, nucleus, cytoplasm...
cytoskeleton, nucleus, cytoplasm
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tribbles pseudokinase 2
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Kaplan plot for TRIB2 in
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*NOTE: the Kaplan plots were collected from OncoLnc