TESK2
Entrez ID: 10420
Full name: testis associated actin remodelling kinase 2
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: TKL: LISK: TESK
Chromosomal location: 1p34.1
Substructure location: Gatekeeper: 130 A-loop: 196...206, 208...221 G-loop: [N/A] αC-helix: [N/A]
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TESK2
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis....
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.
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GO - Biological processes (BP):
actin cytoskeleton organization, focal adhesion assembly, protein phosphorylation, spermatogenesis...
actin cytoskeleton organization, focal adhesion assembly, protein phosphorylation, spermatogenesis
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GO - Molecular function (MF):
ATP binding, metal ion binding, protein kinase activity, protein serine/threonine/tyrosine kinase activity, protein serine/threonine kinase activity, protein tyrosine kinase activity...
ATP binding, metal ion binding, protein kinase activity, protein serine/threonine/tyrosine kinase activity, protein serine/threonine kinase activity, protein tyrosine kinase activity
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GO - Cellular component (CC):
nuclear body, nucleoplasm, nucleus, cytoplasm...
nuclear body, nucleoplasm, nucleus, cytoplasm
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testis associated actin remodelling kinase 2
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Kaplan plot for TESK2 in
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*NOTE: the Kaplan plots were collected from OncoLnc