MKNK1
Entrez ID: 8569
Full name: MAPK interacting serine/threonine kinase 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CAMK: MAPKAPK: MNK
Chromosomal location: 1p33
Substructure location: Gatekeeper: 124 A-loop: 231...261 G-loop: 55...61 αC-helix: 87...101
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MKNK1
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap....
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
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GO - Biological processes (BP):
intracellular signal transduction, peptidyl-serine phosphorylation, protein autophosphorylation, protein phosphorylation, regulation of translation...
intracellular signal transduction, peptidyl-serine phosphorylation, protein autophosphorylation, protein phosphorylation, regulation of translation
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GO - Molecular function (MF):
ATP binding, calcium-dependent protein serine/threonine kinase activity, calmodulin binding, metal ion binding, protein serine/threonine kinase activity...
ATP binding, calcium-dependent protein serine/threonine kinase activity, calmodulin binding, metal ion binding, protein serine/threonine kinase activity
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GO - Cellular component (CC):
cytosol, nucleoplasm, nucleus, cytoplasm...
cytosol, nucleoplasm, nucleus, cytoplasm
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MAPK interacting serine/threonine kinase 1
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Kaplan plot for MKNK1 in
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*NOTE: the Kaplan plots were collected from OncoLnc