SLK
Entrez ID: 9748
Full name: STE20 like kinase
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: STE: STE20: SLK
Chromosomal location: 10q24.33-q25.1
Substructure location: Gatekeeper: 108 A-loop: 172...195 G-loop: 38...48 αC-helix: 41...43
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SLK
Mediates apoptosis and actin stress fiber dissolution....
Mediates apoptosis and actin stress fiber dissolution.
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GO - Biological processes (BP):
activation of protein kinase activity, apoptotic process, cytoplasmic microtubule organization, protein autophosphorylation, regulation of apoptotic process, regulation of cell migration, regulation of focal adhesion assembly, regulation of mitotic cell cycle, signal transduction by protein phosphor...
activation of protein kinase activity, apoptotic process, cytoplasmic microtubule organization, protein autophosphorylation, regulation of apoptotic process, regulation of cell migration, regulation of focal adhesion assembly, regulation of mitotic cell cycle, signal transduction by protein phosphorylation, stress-activated protein kinase signaling cascade
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GO - Molecular function (MF):
ATP binding, cadherin binding, identical protein binding, protein homodimerization activity, protein serine/threonine kinase activity...
ATP binding, cadherin binding, identical protein binding, protein homodimerization activity, protein serine/threonine kinase activity
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GO - Cellular component (CC):
extracellular exosome, cell leading edge, cytoplasm, perinuclear region of cytoplasm...
extracellular exosome, cell leading edge, cytoplasm, perinuclear region of cytoplasm
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STE20 like kinase
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Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
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Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
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Kaplan plot for SLK in
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*NOTE: the Kaplan plots were collected from OncoLnc