BAZ1A
Entrez ID: 11177
Full name: bromodomain adjacent to zinc finger domain 1A
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Atypical: BAZ
Chromosomal location: 14q13.1-q13.2
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
Please click HERE
for better display.
BAZ1A
Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA...
Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.
View more >>
GO - Biological processes (BP):
chromatin remodeling, DNA-dependent DNA replication, histone acetylation, regulation of transcription by RNA polymerase II...
chromatin remodeling, DNA-dependent DNA replication, histone acetylation, regulation of transcription by RNA polymerase II
View more >>
GO - Molecular function (MF):
metal ion binding...
metal ion binding
View more >>
GO - Cellular component (CC):
ACF complex, CHRAC...
ACF complex, CHRAC
View more >>
bromodomain adjacent to zinc finger domain 1A
Control panel
Show dataset:
Show substructure:
All sites
Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
Filter mutation sites
All sites
Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
Data table is loading....
Kaplan plot for BAZ1A in
Download patient group data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from OncoLnc