SRPK3
Entrez ID: 26576
Full name: SRSF protein kinase 3
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CMGC: SRPK
Chromosomal location: Xq28
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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SRPK3
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle...
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity).
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GO - Biological processes (BP):
cell differentiation, intracellular signal transduction, muscle tissue development, regulation of gene expression, regulation of mRNA processing, skeletal muscle tissue development, spliceosomal complex assembly...
cell differentiation, intracellular signal transduction, muscle tissue development, regulation of gene expression, regulation of mRNA processing, skeletal muscle tissue development, spliceosomal complex assembly
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GO - Molecular function (MF):
ATP binding, protein serine/threonine kinase activity...
ATP binding, protein serine/threonine kinase activity
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GO - Cellular component (CC):
nucleus, cytoplasm...
nucleus, cytoplasm
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SRSF protein kinase 3
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Kaplan plot for SRPK3 in
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*NOTE: the Kaplan plots were collected from OncoLnc