MOK
Entrez ID: 5891
Full name: MOK protein kinase
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CMGC: RCK: MOK
Chromosomal location: 14q32.31
Substructure location: Gatekeeper: 82 A-loop: 144...166 G-loop: [N/A] αC-helix: [N/A]
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MOK
Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner....
Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner.
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GO - Biological processes (BP):
intracellular signal transduction, protein phosphorylation, regulation of gene expression, signal transduction...
intracellular signal transduction, protein phosphorylation, regulation of gene expression, signal transduction
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GO - Molecular function (MF):
ATP binding, cyclin-dependent protein serine/threonine kinase activity, metal ion binding, protein kinase activity, protein serine/threonine kinase activity...
ATP binding, cyclin-dependent protein serine/threonine kinase activity, metal ion binding, protein kinase activity, protein serine/threonine kinase activity
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GO - Cellular component (CC):
nucleus, ciliary base, cilium, cytoplasm...
nucleus, ciliary base, cilium, cytoplasm
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MOK protein kinase
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Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
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Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
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Kaplan plot for MOK in
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*NOTE: the Kaplan plots were collected from OncoLnc