MAP4K5
Entrez ID: 11183
Full name: mitogen-activated protein kinase kinase kinase kinase 5
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: STE: STE20: KHS
Chromosomal location: 14q22.1
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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MAP4K5
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway....
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
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GO - Biological processes (BP):
activation of JUN kinase activity, activation of protein kinase activity, intracellular signal transduction, MAPK cascade, protein phosphorylation, regulation of mitotic cell cycle, signal transduction by protein phosphorylation, stress-activated protein kinase signaling cascade...
activation of JUN kinase activity, activation of protein kinase activity, intracellular signal transduction, MAPK cascade, protein phosphorylation, regulation of mitotic cell cycle, signal transduction by protein phosphorylation, stress-activated protein kinase signaling cascade
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GO - Molecular function (MF):
ATP binding, MAP kinase kinase kinase kinase activity, protein kinase activity, protein serine/threonine kinase activity...
ATP binding, MAP kinase kinase kinase kinase activity, protein kinase activity, protein serine/threonine kinase activity
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GO - Cellular component (CC):
cytoplasm...
cytoplasm
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mitogen-activated protein kinase kinase kinase kinase 5
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αC-helix
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A-loop
G-loop
αC-helix
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Minimum 5 samples
Minimum 10 samples
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Kaplan plot for MAP4K5 in
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*NOTE: the Kaplan plots were collected from OncoLnc