CERT1
Entrez ID: 10087
Full name: ceramide transporter 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Atypical: Col4A3BP
Chromosomal location: 5q13.3
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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CERT1
Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner....
Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.
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GO - Biological processes (BP):
cell morphogenesis, cell population proliferation, ceramide metabolic process, ceramide transport, endoplasmic reticulum organization, ER to Golgi ceramide transport, heart morphogenesis, immune response, intermembrane lipid transfer, intermembrane sphingolipid transfer, in utero embryonic developme...
cell morphogenesis, cell population proliferation, ceramide metabolic process, ceramide transport, endoplasmic reticulum organization, ER to Golgi ceramide transport, heart morphogenesis, immune response, intermembrane lipid transfer, intermembrane sphingolipid transfer, in utero embryonic development, lipid homeostasis, mitochondrion morphogenesis, muscle contraction, response to endoplasmic reticulum stress, signal transduction, sphingolipid biosynthetic process
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GO - Molecular function (MF):
ceramide 1-phosphate binding, ceramide 1-phosphate transfer activity, ceramide binding, ceramide transfer activity, kinase activity, lipid binding, phosphatidylinositol-4-phosphate binding...
ceramide 1-phosphate binding, ceramide 1-phosphate transfer activity, ceramide binding, ceramide transfer activity, kinase activity, lipid binding, phosphatidylinositol-4-phosphate binding
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GO - Cellular component (CC):
cytosol, endoplasmic reticulum membrane, Golgi apparatus, mitochondrion, nucleoplasm, membrane...
cytosol, endoplasmic reticulum membrane, Golgi apparatus, mitochondrion, nucleoplasm, membrane
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ceramide transporter 1
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Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
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Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
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Kaplan plot for CERT1 in
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*NOTE: the Kaplan plots were collected from OncoLnc