NTRK3
Drug: AZD1332
Cancer code: SCLC
Cancer type: lung_small_cell_carcinoma
Drug treatment table
| Cell line ID |
Cell line name |
Mutation in substructure |
IC50(uM) |
| SIDM00730 | NCI-H2227 | A_loop (704) | 1.8186 |
| SIDM00730 | NCI-H2227 | A_loop (704) | 210.4809 |
| SIDM00865 | DMS-114 | None | 1.1612 |
| SIDM00522 | DMS-273 | None | 11.1335 |
| SIDM00654 | NCI-H1048 | None | 3.054 |
| SIDM00653 | NCI-H1092 | None | 56.5103 |
| SIDM00642 | NCI-H1417 | None | 8.4746 |
| SIDM00741 | NCI-H1694 | None | 97.0487 |
| SIDM00767 | NCI-H187 | None | 139.1024 |
| SIDM00735 | NCI-H2029 | None | 34.8681 |
| SIDM00706 | NCI-H209 | None | 19.3673 |
| SIDM00699 | NCI-H2141 | None | 18.0447 |
| SIDM00719 | NCI-H345 | None | 187.4046 |
| SIDM00965 | NCI-H446 | None | 2.8988 |
| SIDM01128 | NCI-H526 | None | 37.9447 |
| SIDM01121 | NCI-H69 | None | 32.3306 |
| SIDM01131 | NCI-H82 | None | 6.3778 |
| SIDM00293 | LU-139 | None | 139.4005 |
| SIDM00368 | SBC-5 | None | 14.7759 |
| SIDM00365 | SBC-1 | None | 15.0519 |
| SIDM00294 | LU-135 | None | 6.971 |
| SIDM01078 | SHP-77 | None | 12.2822 |
| SIDM00953 | CPC-N | None | 20.4883 |
| SIDM00524 | DMS-79 | None | 105.5789 |
| SIDM00223 | IST-SL1 | None | 10.7873 |
| SIDM00230 | IST-SL2 | None | 82.3079 |
| SIDM00183 | LB647-SCLC | None | 23.3387 |
| SIDM00296 | LU-134-A | None | 9.201 |
| SIDM00292 | LU-165 | None | 21.7196 |
| SIDM00245 | MS-1 | None | 27.5499 |
| SIDM00648 | NCI-H1304 | None | 9.4917 |
| SIDM00367 | SBC-3 | None | 0.8349 |
| SIDM00506 | COR-L88 | None | 113.6326 |
| SIDM00523 | DMS-53 | None | 3.0986 |
| SIDM00652 | NCI-H1105 | None | 55.687 |
| SIDM00697 | NCI-H1436 | None | 115.4408 |
| SIDM00710 | NCI-H2081 | None | 39.9684 |
| SIDM01129 | NCI-H524 | None | 6.8378 |
| SIDM00143 | COLO-668 | None | 24.5262 |
| SIDM00698 | NCI-H146 | None | 28.3813 |
| SIDM00511 | COR-L279 | None | 7.3824 |
| SIDM00770 | NCI-H1836 | None | 18.8029 |
| SIDM00761 | NCI-H196 | None | 31.3316 |
| SIDM00704 | NCI-H211 | None | 22.6611 |
| SIDM01134 | NCI-H841 | None | 15.8608 |
| SIDM01149 | NCI-H847 | None | 1.9688 |
| SIDM00521 | COR-L95 | None | 42.4365 |
| SIDM00792 | NCI-H1688 | None | 10.0487 |
| SIDM01156 | SW1271 | None | 5.8065 |
| SIDM00508 | COR-L32 | None | 17.5997 |
| SIDM00646 | NCI-H1341 | None | 1.6558 |
| SIDM00766 | NCI-H1876 | None | 9.2132 |
| SIDM00711 | NCI-H2066 | None | 42.312 |
| SIDM00509 | COR-L311 | None | 14.1649 |
| SIDM00865 | DMS-114 | None | 22.199 |
| SIDM00522 | DMS-273 | None | 22.0231 |
| SIDM00654 | NCI-H1048 | None | 41.0682 |
| SIDM00653 | NCI-H1092 | None | 219.9148 |
| SIDM00642 | NCI-H1417 | None | 45.0863 |
| SIDM00741 | NCI-H1694 | None | 196.5701 |
| SIDM00760 | NCI-H1963 | None | 30.7945 |
| SIDM00735 | NCI-H2029 | None | 34.5958 |
| SIDM00706 | NCI-H209 | None | 43.2251 |
| SIDM00699 | NCI-H2141 | None | 43.0631 |
| SIDM00719 | NCI-H345 | None | 394.9709 |
| SIDM00965 | NCI-H446 | None | 6.8619 |
| SIDM01128 | NCI-H526 | None | 9.2074 |
| SIDM01131 | NCI-H82 | None | 20.2362 |
| SIDM00293 | LU-139 | None | 259.116 |
| SIDM00368 | SBC-5 | None | 73.3693 |
| SIDM00294 | LU-135 | None | 15.5436 |
| SIDM01078 | SHP-77 | None | 57.0114 |
| SIDM00953 | CPC-N | None | 49.074 |
| SIDM00524 | DMS-79 | None | 24.2956 |
| SIDM00230 | IST-SL2 | None | 204.0663 |
| SIDM00292 | LU-165 | None | 555.6119 |
| SIDM00245 | MS-1 | None | 18.7102 |
| SIDM00367 | SBC-3 | None | 2.8095 |
| SIDM00523 | DMS-53 | None | 43.946 |
| SIDM01129 | NCI-H524 | None | 3.6006 |
| SIDM00143 | COLO-668 | None | 24.4269 |
| SIDM00721 | NCI-H250 | None | 374.064 |
| SIDM00761 | NCI-H196 | None | 158.5288 |
| SIDM00704 | NCI-H211 | None | 37.1645 |
| SIDM01134 | NCI-H841 | None | 44.0114 |
| SIDM01156 | SW1271 | None | 36.1371 |
| SIDM00766 | NCI-H1876 | None | 3.3189 |