Gene: CECR2

Basic information

Tag Content
Uniprot ID A0A2I3SEK4
Entrez ID 470135
Genbank protein ID
Genbank nucleotide ID XM_009437720.2
Ensembl protein ID ENSPTRP00000075424
Ensembl nucleotide ID ENSPTRG00000014037
Gene name CECR2 histone acetyl-lysine reader
Gene symbol CECR2
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MYKEDPVQGK SNGELSLSRE SEGQKNVSSI PGKTGKRRGR PPKRKKLQEE ILLSEKQEEN 60
SLASEPQTRH GSQGPGQGTW WLLCQTEEEW RQVTESFRER TSLRERQLYK LLSEDFLPEI 120
CNMIAQKGKR PQRTKAELHP RWMSDHLSIK PVKQEETPVL TRIEKQKRKE EEEERQILLA 180
VQKKEQEQML KEERKRELEE KVKAVEDRAK RRKLREERAW LLAQGKELPP ELSHLDPNSP 240
MREEKKTKDL FELDDDFTAM YKVLDVVKAH KDSWPFLEPV DESYAPNYYQ IIKAPMDISS 300
MEKKLNGGLY CTKEEFVNDM KTMFRNCRKY NGESSEYTKM SDNLERCFHR AMMKHFPGED 360
GDTDEEFWIR EDEKREKRRS RAGRSGGSHV WTRSRDPEGP SRKQQPMENG GKSLPPTRRA 420
PSSGDDQSSS STQPLREVGT SNGRGFSHPL HCGGTPSQAP FLNQMRPAVP GTFGPLRGSD 480
PATLYGSCGV PEPHPGEPVQ QRQPFTMQPP AGINSLRGPR LGTPEEKQMC GGLTHLSNMG 540
PHPGSLQLGQ ISGPSQDGSM YAPAQFQPGF IPPRHGGAPA RPPDFPESSE IPPSHMYRSY 600
KYLNRVHSAV WNGNHGATNQ GPLGPDEKPH LGPGPSHQPR TLGHVMDSRV MRPPVPPNQW 660
TEQSGFLPHG VPSSGYMRPP CKSAGHRLQP PTVPAPSSLF GAPAQALRGV QGGDSMMDSP 720
EMIAMQQLSS RVCPPGVPYH PHQPAHPRLP GPFPQVAHPM SVTVSAPKPA LGNPGRAPEN 780
SEAQEPENDQ AEPLPGLEEK PPGVGTSEGV YLTQLPHPTP PLQTDCTRQS SPQERETVGP 840
ELKSSSSESA DNCKAMKGKN PWPSDSSYPG PAAQGCVRDL STVADRGALS ENGVIGEASP 900
CGSEGKGLGS SGSEKLLCPR GRTLQETMPC TGQNAATPPS TDPGLTGGTV SQFPPLYMPG 960
LEYPNSAAHY HISPGLQGVG PVMGGKSPAS HPQHFPPRGF QSTHPHSGGF PRYRPPQGMR 1020
YSYHPPPQPS YHHYQRTPYY ACPQSFSDWQ RPLHPQGSPS GPPASQPPPP RSLFSDKNAM 1080
ASLQGCETLN AALTSPTRMD AVAAKVPNDG QNPGPEEEKL DESMERPESP KEFLDLDNHN 1140
AATKRQSSLS ASEYLYGTPP PPLSSGMGFG SSAFPPHGVM LQTGPPYTPQ RPASHFQPRA 1200
YSSPVAALPP HHPGATQPNG LSQEGPIYRC QEEGLGHFQA VMMEQIGTRS GIRGPFQEMY 1260
RPSGMQMHPV QSQASFPKTP TAATSQEEVP PHKPPTLPLD QS 1302

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCECR2A0A452ELZ1Capra hircusPredictionMore>>
1:1 orthologCECR227443Q9BXF3Homo sapiensPredictionMore>>
1:1 orthologCecr2330409E9Q2Z1CPOMus musculusPublicationMore>>
1:1 orthologCECR2470135A0A2I3SEK4Pan troglodytesPredictionMore>>
1:1 orthologCECR2100356626G1SS27Oryctolagus cuniculusPredictionMore>>
1:1 orthologCecr2500308F1LYI0Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0090537 CERF complex
GO:0043044 ATP-dependent chromatin remodeling

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0103 Bromodomain
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR029614 CECR2

PROSITE

PROSITE ID PROSITE Term
PS00633 BROMODOMAIN_1
PS50014 BROMODOMAIN_2

Pfam

Pfam ID Pfam Term
PF00439 Bromodomain