Gene: Cecr2

Basic information

Tag Content
Uniprot ID F1LYI0
Entrez ID 500308
Genbank protein ID
Genbank nucleotide ID NM_001191977.1
Ensembl protein ID ENSRNOP00000015499
Ensembl nucleotide ID ENSRNOG00000011566
Gene name CECR2, histone acetyl-lysine reader
Gene symbol Cecr2
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MCPEEGGAAG LGELRSWWEV PAIAHFCSLF RTAFRLPDFE IEELEAALHR DDVDFISDLI 60
ACLLQGCYQR RDITPQTFHS YLEDIINYRW ELEEGKPNPL REASFQDLPL RTRVEILHRL 120
CDYRLDADDV FDLLKGLDAD SLRVEPLGED NSGALYWYFY GTRMYKEDPV QGRSNGELSL 180
SRESERQKNV SNVPGKTGKR RGRPPKRKKL QEEIISSEKQ EENSLTSDLQ TRNGSRGPGQ 240
GTWWLLCQTE EEWRQVTESF RERTSLRERQ LYKLLSEDFL PEICNMIAQK GKRPQRTKPE 300
LQHRFMSDHL SIKSTKLEET PMLTKIEKQK RKEEEEERQL LLAVQKKEQE QMLKEERKRE 360
LEEKVKAVED RAKRRKLREE RAWLLAQGKE LPPELSHLDL NSPMREGKKT KDIFELDDDF 420
TAMYKVLDVV KAHKDSWPFL EPVDESYAPN YYQIIKIPMD ISSMEKKLNG GLYCTKEEFV 480
NDMKTMFRNC RKYNGDSSEY TKMSENLERC FHRAMTKHFP GEDGDTDEEF WIREDEKREK 540
RRSRAGRSSG SHVWTRSRDT EGSSRKQPPM ENGGKSLPPA RRAASSGDDQ SSSSIQLPPE 600
RPAASGTFGS LQGSDPTNLH GSSRIPEVPP GEPLQHPPFA IQAPVGISNH RGSRLSAPEE 660
KMCGGLTHLS NMGSHVPSLQ LGQMNCNSQD GNIYPPAPFQ AGFIPSRHGG TPARPPDFPE 720
SSEIPPSHIY HSYKYLNRVH PAVWNGNHGT TNPGRLGPDE KPLVGPGASH HPHALGHMMD 780
GRVMRQPIPP NQWTKQSSFL PPGVPSSGYM QPPCKSAGHR LQPPPTPAPS PRFRGPSQAL 840
RGAQGGESMM DSPEMIAMQQ LSSRVCPPGV PYHPRQPTPP QLPGPFPQVA HSASVCVSAP 900
KPALDNPGST QEISETQEPE GDRAEPVPGL EEKAASICSS EGLYLKQLPH PAPPLSASCT 960
RQSSPHERET EDSQLKSDAS DSADTYKASK NKNPWPLDNS YNSAAVQGAL HGGRDLAIVT 1020
ERGNLPENGV VGEASPCRSE GKGLGGSGSE KPLCPRGKTL QETVPCTGQN ATTPPCTDPN 1080
LMAGTVNQFS PLYMPGIEYS NSATHYPMSP SLQGLGSMMG AKSPGSQPQS FSPRSFQANG 1140
PHPGLFPRYR PQQGMRYSYQ PSSQPSYHPY QRTPYYTCPQ GFSDWQRSLP SQRSPSGPPG 1200
SHPPRPLFSD KNALTSLQGC ETLNAALTSP TQMDAVAAKV VPPDGHNSGP EEEKMDESME 1260
RPESPKEFLD LDNHNAATKR QSSLSTNDYL YGAPPPPLSS GMTFGSSAFP PHSVMLQTGS 1320
PYTPQRSASH FQPRAYASPV PAHPPPHPVA TQPNGLSPEG PLYCCQEEGL GHFQAAMMEQ 1380
TGTGSGIRGS FQDAHRPPGL QMHPIQSQSL FPKTPAPAAS PEQLPPHKAP TLPLDQS 1437

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCECR2A0A452ELZ1Capra hircusPredictionMore>>
1:1 orthologCECR227443Q9BXF3Homo sapiensPredictionMore>>
1:1 orthologCecr2330409E9Q2Z1CPOMus musculusPublicationMore>>
1:1 orthologCECR2470135A0A2I3SEK4Pan troglodytesPredictionMore>>
1:1 orthologCECR2100356626G1SS27Oryctolagus cuniculusPredictionMore>>
1:1 orthologCecr2500308F1LYI0Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0090537 CERF complex
GO:0031010 ISWI-type complex
GO:0005719 nuclear euchromatin
GO:0005634 nucleus
GO:0043044 ATP-dependent chromatin remodeling
GO:0090102 cochlea development
GO:0097194 execution phase of apoptosis
GO:0060122 inner ear receptor cell stereocilium organization
GO:0001842 neural fold formation
GO:0001843 neural tube closure
GO:0021915 neural tube development
GO:0007338 single fertilization

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0103 Bromodomain
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR029614 CECR2

PROSITE

PROSITE ID PROSITE Term
PS00633 BROMODOMAIN_1
PS50014 BROMODOMAIN_2

Pfam

Pfam ID Pfam Term
PF00439 Bromodomain