Gene: ESRRG

Basic information

Tag Content
Uniprot ID A0A2I3T916; A0A2J8QV52;
Entrez ID 457738
Genbank protein ID
Genbank nucleotide ID XM_016938665.1
Ensembl protein ID ENSPTRP00000085369
Ensembl nucleotide ID ENSPTRG00000023622
Gene name Estrogen related receptor gamma
Gene symbol ESRRG
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MWRECDWGLG AVKSDLACVP SAKRLLCRMS NKDRHIDSSC SSFIKTEPSS PASLTDSVNH 60
HSPGGSSDAS GSYSSTMNGH QNGLDSPPLY PSAPILGGSG PVRKLYDDCS STIVEDPQTK 120
CEYMLNSMPK RLCLVCGDIA SGYHYGVASC EACKAFFKRT IQGNIEYSCP ATNECEITKR 180
RRKSCQACRF MKCLKVGMLK EGVRLDRVRG GRQKYKRRID AENSPYLNPQ LVQPAKKPLL 240
WSDPADNKIV SHLLVAEPEK IYAMPDPTVP DSDIKALTTL CDLADRELVV IIGWAKHIPG 300
FSTLSLADQM SLLQSAWMEI LILGVVYRSL SFEDELVYAD DYIMDEDQSK LAGLLDLNNA 360
ILQLVKKYKS MKLEKEEFVT LKAIALANSD SMHIEDVEAV QKLQDVLHEA LQDYEAGQHM 420
EDPRRAGKML MTLPLLRQTS TKAVQHFYNI KLEGKVPMHK LFLEMLEAKV

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologESRRG478961J9NWD9Canis lupus familiarisPredictionMore>>
1:1 orthologESRRGA0A452FEX0Capra hircusPredictionMore>>
1:1 orthologESRRG2104P62508Homo sapiensPublicationMore>>
1:1 orthologEsrrg26381P62509Mus musculusPredictionMore>>
1:1 orthologESRRG457738A0A2I3T916Pan troglodytesPredictionMore>>
1:1 orthologESRRG100355568G1SEH2Oryctolagus cuniculusPredictionMore>>
1:1 orthologEsrrg360896P62510Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0042025 host cell nucleus
GO:0005634 nucleus
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0004879 nuclear receptor activity
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0005496 steroid binding
GO:0003707 steroid hormone receptor activity
GO:0008270 zinc ion binding
GO:0120162 positive regulation of cold-induced thermogenesis
GO:0048384 retinoic acid receptor signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0479 Metal-binding
KW-0539 Nucleus
KW-0675 Receptor
KW-1185 Reference proteome
KW-0804 Transcription
KW-0805 Transcription regulation
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR035500 NHR-like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR027289 Oest-rel_rcp
IPR024178 Oest_rcpt/oest-rel_rcp
IPR003078 Retinoic_acid_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA

PROSITE

PROSITE ID PROSITE Term
PS51843 NR_LBD
PS00031 NUCLEAR_REC_DBD_1
PS51030 NUCLEAR_REC_DBD_2

Pfam

Pfam ID Pfam Term
PF00104 Hormone_recep
PF00105 zf-C4