Gene: MAPK3

Basic information

Tag Content
Uniprot ID A0A3Q1MNN7
Entrez ID 531391
Genbank protein ID
Genbank nucleotide ID NM_001110018.1
Ensembl protein ID ENSBTAP00000071185
Ensembl nucleotide ID ENSBTAG00000016156
Gene name Mitogen-activated protein kinase
Gene symbol MAPK3
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAAAAAAQGG GEIVKGQPFD VGPRYTQLQY IGEGAYGMVS SAYDHVRKTR VAIKKISPFE 60
HQTYCQRTLR EIQILLRFRH ENVIGIRDIL RAPTLEAMRD VYIVQDLMET DLYKLLKSQQ 120
LSNDHVCYFL YQILRGLKYI HSANVLHRDL KPSNLLINTT CDLKICDFGL ARIADPEHDH 180
TGFLTEYVAT RWYRAPEIML NSKGYTKSID IWSVGCILAE MLSNRPIFPG KHYLDQLNHI 240
LGILGSPSQE DLNCIINMKA RNYLQSLPSK TKVAWAKLFP KSDPKALDLL DRMLTFNPNK 300
RITVEEALAH PYLEQYYDPT DEPVAEEPFT FDMELDDLPK ERLKELIFQE TARFQPGVLE 360
AS 362

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMAPK3531391A0A3Q1MNN7Bos taurusPredictionMore>>
1:1 orthologMAPK3A0A452ETI1Capra hircusPredictionMore>>
1:1 orthologMAPK35595P27361Homo sapiensPredictionMore>>
1:1 orthologMapk326417Q63844CPOE13.5, E14.5, E15.5, E16.5Mus musculusPublicationMore>>
1:1 orthologMAPK3454037H2RA86Pan troglodytesPredictionMore>>
1:1 orthologA0A480NH74Sus scrofaPredictionMore>>
1:1 orthologMapk350689P21708Rattus norvegicusPredictionMore>>
1:1 orthologmapk3399480Q7ZVK8Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005524 ATP binding
GO:0004707 MAP kinase activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0418 Kinase
KW-0460 Magnesium
KW-0547 Nucleotide-binding
KW-1185 Reference proteome
KW-0723 Serine/threonine-protein kinase
KW-0808 Transferase

Interpro

InterPro ID InterPro Term
IPR011009 Kinase-like_dom_sf
IPR003527 MAP_kinase_CS
IPR008349 MAPK_ERK1/2
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS

PROSITE

PROSITE ID PROSITE Term
PS01351 MAPK
PS00107 PROTEIN_KINASE_ATP
PS50011 PROTEIN_KINASE_DOM
PS00108 PROTEIN_KINASE_ST

Pfam

Pfam ID Pfam Term
PF00069 Pkinase