| Tag | Content |
|---|---|
| Uniprot ID | Q7ZVK8 |
| Entrez ID | 399480 |
| Genbank protein ID | AAH45505.1; AAI63960.1; AAY57804.1; AAH66401.1; AAH97073.1; |
| Genbank nucleotide ID | NM_201507.1 |
| Ensembl protein ID | ENSDARP00000094521 |
| Ensembl nucleotide ID | ENSDARG00000070573 |
| Gene name | Mitogen-activated protein kinase |
| Gene symbol | mapk3 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAESGSSAAA AGAAGSNSSA AGPGGAVAPG GPSGAAGSKP GLESVKGQNF DVGPRYTDLQ 60 YIGEGAYGMV CSAFDNVNKI RVAIKKISPF EHQTYCQRTL REIKILLRFH HENIIGINDI 120 LRARHIDYMR DVYIVQDLME TDLYKLLKTQ QLSNDHICYF LYQILRGLKY IHSANVLHRD 180 LKPSNLLINT TCDLKICDFG LARIADPEHD HTGFLTEYVA TRWYRAPEIM LNSKGYTKSI 240 DIWSVGCILA EMLSNRPIFP GKHYLDQLNH ILGVLGSPSQ DDLNCIINMK ARNYLQSLPQ 300 KPKIPWNKLF PKADNKALDL LDRMLTFNPL KRINVEQALA HPYLEQYYDP SDEPVAEEPF 360 TFNMELDDLP KEKLKELIFE ETARFQANYQ GS 392 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MAPK3 | 531391 | A0A3Q1MNN7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MAPK3 | A0A452ETI1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MAPK3 | 5595 | P27361 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mapk3 | 26417 | Q63844 | CPO | E13.5, E14.5, E15.5, E16.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | MAPK3 | 454037 | H2RA86 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A480NH74 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Mapk3 | 50689 | P21708 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mapk3 | 399480 | Q7ZVK8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0004707 | MAP kinase activity |
| GO:0106310 | protein serine kinase activity |
| GO:0106311 | protein threonine kinase activity |
| GO:0007420 | brain development |
| GO:0007166 | cell surface receptor signaling pathway |
| GO:0021952 | central nervous system projection neuron axonogenesis |
| GO:0043009 | chordate embryonic development |
| GO:0001654 | eye development |
| GO:0035556 | intracellular signal transduction |
| GO:0010468 | regulation of gene expression |
| Pfam ID | Pfam Term |
|---|---|
| PF00069 | Pkinase |