| Tag | Content |
|---|---|
| Uniprot ID | A0A3Q2HQB9 |
| Entrez ID | 100051502 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005609826.2; XM_001490766.3; |
| Ensembl protein ID | ENSECAP00000037295 |
| Ensembl nucleotide ID | ENSECAG00000007482 |
| Gene name | Interferon regulatory factor 6 |
| Gene symbol | IRF6 |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MALHPRRVRL KPWLVAQVDS GLYPGLIWLH RDSKRFQIPW KHATRHSPQQ EEENTIFKAW 60 AVETGKYQEG VDDPDPAKWK AQLRCALNKS REFNLMYDGT KEVPMNPVKI YQVCDIPQPQ 120 GSIINPGSTG SAPWDEKDND VDEEDEEDEL DQSQHHVPIQ DTFPFLNING SPMAPASVGN 180 CSVGNCSPEA VWPKTEPLEM EVPQTPIQPF YSSPELWISS LPMTDLDIKF QYRGKEYGQT 240 MTVSNPQGCR LFYGDLGPMP DQEELFGPVS LEQVKFPGPE HITNEKQKLF TSKLLDVMDR 300 GLILEVSGHA IYAIRLCQCK VYWSGPCAPS LVAPNLIERQ KKVKLFCLET FLSDLIAHQK 360 GQIEKQPPFE IYLCFGEEWP DGKPLERKLI LVQVIPVVAR MIYEMFSGDF TRSFDSGSVR 420 LQISTPDIKD NIVAQLKQLY RILQTQESWQ PMQPTPSMQL PPALPAQ 467 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | IRF6 | 102190443 | A0A452EQT2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | IRF6 | 100051502 | A0A3Q2HQB9 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | IRF6 | 3664 | O14896 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Irf6 | 54139 | P97431 | CPO | E14.0, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | IRF6 | 457701 | A0A2I3TSL3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | IRF6 | 397521 | E9LK28 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Irf6 | 364081 | D4AAV0 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | irf6 | 393570 | Q6PGZ7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030054 | cell junction |
| GO:0005829 | cytosol |
| GO:0005654 | nucleoplasm |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0043565 | sequence-specific DNA binding |
| GO:0044212 | transcription regulatory region DNA binding |
| GO:0007050 | cell cycle arrest |
| GO:0048468 | cell development |
| GO:0030216 | keratinocyte differentiation |
| GO:0043616 | keratinocyte proliferation |
| GO:0060644 | mammary gland epithelial cell differentiation |
| GO:0008285 | negative regulation of cell population proliferation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0060021 | roof of mouth development |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |