| Tag | Content |
|---|---|
| Uniprot ID | A0A452EQT2 |
| Entrez ID | 102190443 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018060775.1 |
| Ensembl protein ID | ENSCHIP00000014522 |
| Ensembl nucleotide ID | ENSCHIG00000015540 |
| Gene name | IRF tryptophan pentad repeat domain-containing protein |
| Gene symbol | IRF6 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MALHPRRVRL KPWLVAQVDS GLYPGLIWLH RDSKRFQIPW KHATRHSPQQ EEENTIFKAW 60 AVETGKYQEG VDDPDPAKWK AQLRCALNKS REFNLMYDGT KEVPMNPVKI YQVCDIPQPQ 120 GSIINPGSTG SAPWDEKDND VDEEDEEDEL DQSQHHVPIQ DTFPFLNING SPIAPGSVGN 180 CSVGNCSPEA VWPKTEPLEM EVPQAPIQPF YSSPELWISS LPMTDLDIKF QYRGKEYGQT 240 MTVSNPQGCR LFYGDLGPMP DQEELFGPVS LEQVKFPGPE HITNEKQKLF TSKLLDVMDR 300 GLILEVSGHA IYAIRLCQCK VYWSGPCAPS LVAPNLIERQ KKVKLFCLET FLSDLIAHQK 360 GQIEKQPPFE IYLCFGEEWP DGKPQERKLI LVQVIPVVAR MIYEMFSGDF TRSFDSGSVR 420 LQISTPDIKD NIVAQLKQLY RILQTQESWQ PMQPAPSMQL PAALPTQ 467 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | IRF6 | 102190443 | A0A452EQT2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | IRF6 | 100051502 | A0A3Q2HQB9 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | IRF6 | 3664 | O14896 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Irf6 | 54139 | P97431 | CPO | E14.0, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | IRF6 | 457701 | A0A2I3TSL3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | IRF6 | 397521 | E9LK28 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Irf6 | 364081 | D4AAV0 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | irf6 | 393570 | Q6PGZ7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0044212 | transcription regulatory region DNA binding |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |