| Tag | Content |
|---|---|
| Uniprot ID | Q6PGZ7 |
| Entrez ID | 393570 |
| Genbank protein ID | AAU85359.1; AAX57954.1; AAH56772.1; |
| Genbank nucleotide ID | NM_200598.2 |
| Ensembl protein ID | ENSDARP00000139404 |
| Ensembl nucleotide ID | ENSDARG00000101986 |
| Gene name | Interferon regulatory factor 6 |
| Gene symbol | irf6 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSSHPRRVRL KPWLVSQVDN ATFPGLVWLD RDAKRFQIPW KHATRHTPQQ EEENTIFKAW 60 AVETGKYQEG VDEPDPAKWK AQLRCALNKS REFNLIYDGT KEVPMNPLKI YDVCDIPQTP 120 SNPGSVPTYE TDGDEDDIPD TPEPPPPYAS HGMSASPLAA VWTPPGSVSP LQPSSCAPPP 180 ALPPPPALPP PAATVLPAAA APPANVWPKK EPEDVEMQPP PMEIQTPTAL DNLFITPETW 240 ISSLPMTDLE VQFYYRGKEV CPPLTVSNPQ GCRLFYGDLG PIVNQEELFG PVSLEQVRFP 300 PTEHIANDKQ RVFTSRLLDV MDRGLILEVS GHDIYAVRLC QCKVYWSGPC APNPNAPNLI 360 ERQQKVKLFC LESFLSGVIT HQRGQSSDAP LYDIHLCFGE EWPDGRPRER KLIMVQVVPV 420 VARMISEMFS GDCTRSFDSG SVRLQISIPD IKDNIVTHLK QLYRLLQTHQ GPENWPLPPG 480 AALQLSSALH TQ 492 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | IRF6 | 102190443 | A0A452EQT2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | IRF6 | 100051502 | A0A3Q2HQB9 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | IRF6 | 3664 | O14896 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Irf6 | 54139 | P97431 | CPO | E14.0, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | IRF6 | 457701 | A0A2I3TSL3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | IRF6 | 397521 | E9LK28 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Irf6 | 364081 | D4AAV0 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | irf6 | 393570 | Q6PGZ7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0048702 | embryonic neurocranium morphogenesis |
| GO:0060429 | epithelium development |
| GO:0002376 | immune system process |
| GO:0006357 | regulation of transcription by RNA polymerase II |