Gene: GAS1

Basic information

Tag Content
Uniprot ID A0A452DUH3
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000003426
Ensembl nucleotide ID ENSCHIG00000007592
Gene name Growth arrest specific 1
Gene symbol GAS1
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
EKAGLLGGGG GARRGTVPGA WLCLMALLQL LGSAPRGSGL AHGRRLICWQ ALLQCQGEPE 60
CSYAYNQYAE ACAPVLAQRG GSDVPGAAAA AAAFPASAAS FSSRWRCPSH CISALIQLNH 120
TRRGPALEDC DCAQDENCKS TKRAIEPCLP RTSGGGAGGP GAGAGGVLGC TEARRRCDRD 180
SRCNLALSRY LTYCGKLFNG LRCTDECRTV IEDMLAMPKA ALLNDCVCDG LERPICESVK 240
ENMARLCFGA ELGNGPGSSG SDGGLDDYYD EEYDDEQRTG GTGGEQPLDD DDGVPHPPRP 300
GGGAAAAGGR GDLPYGPGRR SSGGGGCRSA PRSAWTLFAS ILLLPLLF 348

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologGAS1A0A452DUH3Capra hircusPredictionMore>>
1:1 orthologGAS12619P54826Homo sapiensPredictionMore>>
1:1 orthologGas114451Q01721CPOE13.0, E14.5Mus musculusPublicationMore>>
1:1 orthologGAS1A0A2I3SJR6Pan troglodytesPredictionMore>>
1:1 orthologGas1683470M0RBH9Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005886 plasma membrane
GO:0007050 cell cycle arrest
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0045930 negative regulation of mitotic cell cycle
GO:0010955 negative regulation of protein processing
GO:0060628 regulation of ER to Golgi vesicle-mediated transport

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR039596 GAS1
IPR016017 GDNF/GAS1

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF02351 GDNF