| Tag | Content |
|---|---|
| Uniprot ID | M0RBH9 |
| Entrez ID | 683470 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_003751637.4; XM_001066058.6; |
| Ensembl protein ID | ENSRNOP00000066915 |
| Ensembl nucleotide ID | ENSRNOG00000050485 |
| Gene name | Growth arrest-specific 1 |
| Gene symbol | Gas1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDEDAHARSA RNSDKLFQRP RGRHPSLVSA PHRVRRPLLP AMLAALLGGG GARSGSLPGA 60 LLCLMALLQL LGSAPRGSGL AHGRRLICWQ ALLQCQGEPD CSYAYSQYAE ACAPVLAQRG 120 GADAPGPAGA FPSSAASFSP RWRCPSHCIS ALIQLNHTRR GPALEDCDCA QDEHCRSTKR 180 AIEPCLPRTS SVGPGAGAGS VMGCTEARRR CDRDSRCNLA LGRYLAYCGK LFNGLRCTDE 240 CRAVIEDMLA VPKAALLNDC VCDGLERPIC ESVKENMARL CFGPDASNGP GSSGSDGGLD 300 DYYDEEYDDE QRAGAAGGEQ PLDDDDGLAR PGGGAAGAGG RGDLPHGPGR RSSSSGSGGH 360 WATRSSWTPF ACFLLLLLLG SHL 383 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GAS1 | A0A452DUH3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | GAS1 | 2619 | P54826 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gas1 | 14451 | Q01721 | CPO | E13.0, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | GAS1 | A0A2I3SJR6 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Gas1 | 683470 | M0RBH9 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0046658 | anchored component of plasma membrane |
| GO:0016020 | membrane |
| GO:0005886 | plasma membrane |
| GO:0007411 | axon guidance |
| GO:0043010 | camera-type eye development |
| GO:0007050 | cell cycle arrest |
| GO:0045165 | cell fate commitment |
| GO:0035924 | cellular response to vascular endothelial growth factor stimulus |
| GO:0021587 | cerebellum morphogenesis |
| GO:0048589 | developmental growth |
| GO:0021904 | dorsal/ventral neural tube patterning |
| GO:0009953 | dorsal/ventral pattern formation |
| GO:0048701 | embryonic cranial skeleton morphogenesis |
| GO:0042733 | embryonic digit morphogenesis |
| GO:0048598 | embryonic morphogenesis |
| GO:0048706 | embryonic skeletal system development |
| GO:0048592 | eye morphogenesis |
| GO:0042474 | middle ear morphogenesis |
| GO:0043066 | negative regulation of apoptotic process |
| GO:0030308 | negative regulation of cell growth |
| GO:0050680 | negative regulation of epithelial cell proliferation |
| GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
| GO:0045930 | negative regulation of mitotic cell cycle |
| GO:0010955 | negative regulation of protein processing |
| GO:0045879 | negative regulation of smoothened signaling pathway |
| GO:0042476 | odontogenesis |
| GO:0042473 | outer ear morphogenesis |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0050679 | positive regulation of epithelial cell proliferation |
| GO:0002053 | positive regulation of mesenchymal cell proliferation |
| GO:0045880 | positive regulation of smoothened signaling pathway |
| GO:0012501 | programmed cell death |
| GO:0060628 | regulation of ER to Golgi vesicle-mediated transport |
| GO:0008589 | regulation of smoothened signaling pathway |
| GO:0060021 | roof of mouth development |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |