| Tag | Content |
|---|---|
| Uniprot ID | A0A452ENV0 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000013747 |
| Ensembl nucleotide ID | ENSCHIG00000014923 |
| Gene name | VWFA domain-containing protein |
| Gene symbol | VWA8 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MQSRLLLLGP PGGPPAARRV RLLLRQVVRR QPGGAAPRSE ARLLHAGAGA GSVSDSLAQS 60 VIQHLRWIMQ KDLLGQDVFL IGPPGPLRRS IAMQYLELTK REVEYIALSR DTTETDLKQR 120 REIRAGTAFY IDQCAVRAAT EGRTLILEGL EKAERNVLPV LNNLLENREM QLEDGRFLMS 180 AERYDKLLQD HTKTELDAWK IVRVSENFRV IALGLPVPRY SGNPLDPPLR SRFQARDIYY 240 LPFKDQLKLL YSVGANVPTE KVSQLLSFAT TLCSQESSTL GLPDFPLDSL PAAVQILDSF 300 PMMSVQHALQ WLYPYTVLLG HEGKMAVEGV LKRFELEDSR RSVLPEKIVR VERTTENNVF 360 QASVTIRIAE KEVTIKVPAG TRPLSQPCTS DRFIQTLSHK QLLAEMMQSH MVKDICLIGG 420 KGCGKTVIAK NFADTLGYNI EPIMLYQDMT ARDLLQQRYT LPNGDTAWRS SPLVNAALEG 480 KLVLLDGIHR VNAGTLAVLQ RLIHDRELSL YDGSRLLRED RYTRLKEELQ VSDEQLQQRS 540 IFPVHPSFRI IALAEPPVIG STTQQWLGPE FLTMFFFHYM KPLVKSEEIQ VIKEMVPDMP 600 PVALDKLLSF THKLRETQDP TAQSLAASLS TRQLLRISRR LSQYPNENLH NAVTKACLSR 660 FLPSLARSAL EKNLADAAIE ISTANSPESD LEDYKCEVSS GSLRIGAVSA PIYNAHEKMK 720 VPDVLFYDNI QHMIVMEDML KDFLLGEHLL LVGNQGVGKN KIVDRFLHLL NRPREYIQLH 780 RDTTVQTLTL QPSVKDGLIV YEDSPLVKAV KLGHVLVVDE ADKAPTNVTC ILKTLVENGE 840 MILADGRRIV ANAALVNGRE NVVVIHPDFR MIVLANRPGF PFLGNDFFGT LGDIFSCHAV 900 DNPKPYSELR MLRQYGPNVP EPILQKLVAA FGELRNLADQ GIINYPYSTR EVVNIVKHLQ 960 KFPTEGLSSV VRNVFDFDSY NNDMREILIN TLHKYGIPIG AKPSNVQLAK ELPLPEQTFM 1020 GYWTIGQSRN GMQKLLCPAE THHIDIKGPA LIHIQEYPIE RHEGRSQTFT EECSSWRLPL 1080 DEMNLICDVA TTHENEENIL YVVACNPVSL YFMNMTGKSG HFVDLFDIFP RTASGIWHPF 1140 VTVAPLGNPL KGQVVLHEQQ SNVILLLDPT SQALHRLILP SEEFTMKKTS WWNKEEAETY 1200 KMCKEFSHKN WLVFYKEKGN TLAVLDVLEG RTHTISLPIN LQTVFLVAED KWLLVESKTN 1260 QKYLLTTPAH IESKDSGVCQ LYVLREELPS PGFGVTQETD RSIPHTISSD QLSSENLSLA 1320 VGQKIASPNR ILSDRNSYAT IVVGFPDLMS PSEVYSWKRP SSLSKSRVTD STFYGGKKKS 1380 GTAKQSNCVT LLDTNQIVRI LPPGEVPLKD IYPKDVTPPQ TAGYIEVTDL QSKRLRYIPI 1440 PGSDSLSPYT TWLSTISDTD ALLAKWGRGG VVTVDMGGRV RLWETGLEHL QRSLMEWRNM 1500 IGEGDRHMQI TIERESGEDV SSPKHGKEDP DNMPHVGGNT WAGGTGGRDT AGLGGKGGPY 1560 RLDAGHTVYQ VSQAEKDAVP EEVKRAAREM GQRAFQQRLK EIQMSEYDAA TYERFSGAVR 1620 RQVHSLRIIL DNLQAKGKER QWLRHQATGE LDDAKIIDGL TGEKAIYKRR GELEPQMGSP 1680 QQKPKRLRLV VDVSGSMYRF NGVDGRLERS MEAVCMVMEA FENYEEKFKY DIAGHSGDGY 1740 NIGLVPINKV PKDNKQRLEI LKTMHAHAQF CMSGDHTLEG TEHAIKEIAK EEADEYFVIV 1800 LSDANLSRYG IHPAKFAQIL TSNPQVNAFA IFIGSLGDQA ARLQRTLPAG RSFVAMDTKD 1860 IPQILQQIFT STMLSSV 1877 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | VWA8 | 485463 | F1PD22 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | VWA8 | A0A452ENV0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | VWA8 | 23078 | A3KMH1 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Vwa8 | 219189 | Q8CC88 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | VWA8 | 452560 | H2Q7H4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | VWA8 | I3LJL2 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | VWA8 | G1T8E0 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | vax2 | 561317 | B0R0T1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005524 | ATP binding |
| GO:0016887 | ATPase activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50234 | VWFA |
| Pfam ID | Pfam Term |
|---|---|
| PF07728 | AAA_5 |