| Tag | Content |
|---|---|
| Uniprot ID | F1PD22 |
| Entrez ID | 485463 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005633935.2 |
| Ensembl protein ID | ENSCAFP00000007107 |
| Ensembl nucleotide ID | ENSCAFG00000004764 |
| Gene name | von Willebrand factor A domain containing 8 |
| Gene symbol | VWA8 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MQSRLLLLGA PGGPGGPAAR RVRLLLRQVV RGRPGGAGRA EVRLLQAGAG ADTGETVNIG 60 DVSYKLKTPK SPELVPQNYI SDSVVQSVIQ HLKWMMQKDL LGQDVFLIGP PGPLRRSIAM 120 QYLELTKREV EYIALSRDTT ESDLKQRREI RAGTAFYIDQ CAVRAATEGR TLILEGLEKA 180 ERNVLPVLNN LLENREMQLE DGRFLMSSER YDKLLQDHTK TELDAWKIVR VSENFRVIAL 240 GLPVPKYSGN PLDPPLRSRF QARDIYYLPF KDQLKLLYSV GASVSAEKIS QLLSFATTLC 300 SQESSTLGLP DFPLDSLPAA VQILDSFPMM SIKHAIQWLY PYTILLGHEG KMAVEGVLKR 360 FELQDSDSSM LPKEVVRVER LVDSPAPQAA VTVRIAEKEV TIQVPAGTRP INQPCASDHF 420 IQTLSHKQLL AEMMQSHMVK DICLIGGKGC GKTVIAKNFA DNLGYNIEPI MLYQDMTARD 480 LLQQRYTLPN GDTAWRSSPL VNAALEGKLV LLDGIHRVNA GTLAVLQRLI HDRELSLYDG 540 SRLLREDRYM RLKEELQLSD EQLQKRSIFP VHPSFRIIAL AEPPVIGSTT QQWLGPEFLT 600 MFLFHYMKPL VKSEEIQVIK EMVPNIPQEA LDRLLSFTHK LRETQDPTAQ SLAASLSTRQ 660 LLRISRRLSQ YPNENLHSAV TKACLSRFLP SLARSALEKN LADAEIEIST DNHQEPELEN 720 YKCEIASGNL RIGAISAPIY NTHEKMKVPD VLFYDNLQHM IVMEDMLKDF LLGEHLLLVG 780 NQGVGKNKIV DRFLHLLNRP REYIQLHRDT TVQTLTLQPS VKDGLIVYED SPLVKAVKLG 840 HVLVVDEADK APTNVTCILK TLVENGEMIL ADGRRIVANS ANVNGRENVI VIHPDFRMIV 900 LANRPGFPFL GNDFFGTLGD IFSCHAVDNP KPHSELEMLR QYGPNVPKPI LEKLVAAFGE 960 LRSLADQGII NYPYSTREVV NIVKHLQKFP TEGLSSVVRN VFDFDSYNND MREILINTLH 1020 KYGIPIGAKP TSVQLAKELP LPEQTFMGYW TIGQSRNGIQ KLLCPTETHH IDIKGPALIN 1080 IQEYPIERYE ERSQTFTEEC ASWKLPLDEI NLICDIATSS ENEENTLYVV ACNPITLYFM 1140 NMAGKSGYLV DFSDIFPRTA GRVWHPFVTV APLGNPLKDQ VILHEQQSNV ILLLDTTGQA 1200 LRRLILPSEE VPSKKPSWWS KEDTETYKMC KEFSHKNWLV FYKENGNNLT VLDVLEGRTH 1260 TISLPINLKT VFLVAEDKWL LVEDKTNQKY LLTKPAHIES EDSGVCQLYM LKEEPPSSGF 1320 GVIQETDLSI PHKISSDQLS SENLSSAVGQ KIASPNRILS DKNSYATVVI GFPDLMSPSE 1380 VYSWKRPSSL HKPSVTDTTF YGGKKKSETP KQSNCVTLLD TNQIVRILPP GEVPLKDIYP 1440 KDVTPPQTAG YIEITDLQSK KLRYIPIPRS ESLSPYTTWL STISDTDALL AEWDKGGVVT 1500 VDMGGHIRLW ETGLEHLQRS LMEWRNMIGQ GDRQMQITIH RDSGKDVSSP KHGKEDPDNM 1560 PHVGGNTWAG GTGGRDTAGL GGKGGPYRLD AGHTVYQVSE AEKDAVPEEV KRAAREMGQK 1620 AFQQRLKEIQ MSEYDATTYE RFSGAVRRQV HSLRVILDNL QAKGKERQWL RHQATGELDD 1680 AKIIEGLTGE KAIYKRRGEL EPQLGSPQQK PKRLRLVVDV SGSMYRFNGV DGRLERSMEA 1740 VCMVMEAFEN YEEKFKYDIV GHSGDGYNIG LVPLNKIPKD NKQRLEILKT MHAHAQFCMS 1800 GDHTLEGTEH AIKEIVKEEA DEYFVIVLSD ANLSRYGIHP AKFAQILTSN PQVNAFAIFI 1860 GSLGDQATRL QRTLPAGRSF VAMDTKDIPQ ILQQIFTSTM LSTV 1904 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | VWA8 | 485463 | F1PD22 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | VWA8 | A0A452ENV0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | VWA8 | 23078 | A3KMH1 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Vwa8 | 219189 | Q8CC88 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | VWA8 | 452560 | H2Q7H4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | VWA8 | I3LJL2 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | VWA8 | G1T8E0 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | vax2 | 561317 | B0R0T1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005524 | ATP binding |
| GO:0016887 | ATPase activity |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50234 | VWFA |
| Pfam ID | Pfam Term |
|---|---|
| PF07728 | AAA_5 |