| Tag | Content |
|---|---|
| Uniprot ID | A0A452FGS1 |
| Entrez ID | 102190273 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018062553.1; XM_018062548.1; XM_018062545.1; XM_018062559.1; |
| Ensembl protein ID | ENSCHIP00000023370 |
| Ensembl nucleotide ID | ENSCHIG00000020961 |
| Gene name | Uncharacterized protein |
| Gene symbol | ZEB2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MKQPIMADGP RCKRRKQANP RRKNVVNYDN VVDTGSETDE EDKPQIAEED GIANPLDQER 60 SPASVPNHES SPHVSQALLP REEEEDEIRE GGVEHAWHNS DILQASVDGP EEMKEDYDTM 120 GPEATIQTTV NNGTVKNANC TSDFEEYFAK RKLEERDGHA VSIEEYLQRS DTAIIYPEAP 180 EELSRLGTPE ANGQEENDLP PGTPDAFAQL LTCPYCDRGY KRLTSLKEHI KYRHEKNEEN 240 FSCPLCSYTF AYRTQLERHM VTHKPGTDQH QMLTQGAGNR KFKCTECGKA FKYKHHLKEH 300 LRIHSGEKPY ECPNCKKRFS HSGSYSSHIS SKKCIGLISV NGRMRNNIKT GSSPNSVSSS 360 PTNSAITQLR NKLENGKPLS MSEQTGLLKI KTEPLDFNDY KVLMATHGFS GTSPFMNGAL 420 GATSPLGVHP SAQSPMQHLG VGMEAPLLGF PTMNSNLSEV QKVLQIVDNT VSRQKMDCKA 480 EEISKLKGYH MKDPCSQPEE QGVTSPNIPP VGLPVVSHNG ATKSIIDYTL EKVNEAKACL 540 QSLTTDSRRQ ISNIKKEKLR TLIDLVTDDK MIENHNISTP FSCQFCKESF PGPIPLHQHE 600 RYLCKMNEEI KAVLQPHENI VPNKAGVFVD NKALLLSSVL SEKGMTSPIN PYKDHMSVLK 660 AYYAMNMEPN SDELLKISIA VGLPQEFVKE WFEQRKVYQY SNSRSPSLER NSKPLAPNSN 720 PPTKDSLLPR SPVKPMDSIT SPSIAELHNS VTNCDPPLRL TKPSHFTNIK PVEKLDHSRS 780 NTPSPLNLSS TSSKNSHSSS YTPNSFSSEE LQAEPLDLSL PKQMKEPKSI IATKNKTKVG 840 SINLDHNSVS SSSENSDEPL NLTFIKKEFS NSNNLDSKSA NPVFGMNPFS AKPLYTALPP 900 QSAFPPATFM PPVQTSIPGL RPYPGLDQMS FLPHMAYTYP TGAATFADMQ QRRKYQRKPG 960 FQGELLDGAP DYMSGLDDMT DSDSCLSRKK IKKTESGMYA CDLCDKTFQK SSSLLRHKYE 1020 HTGKRPHQCQ ICKKAFKHKH HLIEHSRLHS GEKPYQCDKC GKRFSHSGSY SQHMNHRYSY 1080 CKREAEEREA AEREAREKGH LEPTELLMNR AYLQSITPQG YSDSEERESM PRDGESEKEH 1140 EKEGEDGYGK LGRQDGDEEF EEEEEESENK SMDTDPETIR DEEETGDHSM DDSSEDGKME 1200 TKSDHEEDNM EDGM 1214 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ZEB2 | 102190273 | A0A452FGS1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ZEB2 | A0A1B0GV02 | Homo sapiens | Prediction | More>> | |||
| 1:1 ortholog | Zeb2 | 24136 | Q9R0G7 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | ZEB2 | 459644 | H2QIS9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A4X1TCF8 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Zeb2 | 311071 | E9PTC3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0000790 | nuclear chromatin |
| GO:0005730 | nucleolus |
| GO:0005654 | nucleoplasm |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0070412 | R-SMAD binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0021846 | cell proliferation in forebrain |
| GO:0048668 | collateral sprouting |
| GO:0021540 | corpus callosum morphogenesis |
| GO:0021957 | corticospinal tract morphogenesis |
| GO:0048066 | developmental pigmentation |
| GO:0021766 | hippocampus development |
| GO:0061373 | mammillary axonal complex development |
| GO:0097324 | melanocyte migration |
| GO:0001755 | neural crest cell migration |
| GO:0001843 | neural tube closure |
| GO:0050772 | positive regulation of axonogenesis |
| GO:0043507 | positive regulation of JUN kinase activity |
| GO:1902748 | positive regulation of lens fiber cell differentiation |
| GO:0045636 | positive regulation of melanocyte differentiation |
| GO:0030177 | positive regulation of Wnt signaling pathway |
| GO:1903056 | regulation of melanosome organization |
| GO:0001756 | somitogenesis |