Gene: NECTIN1

Basic information

Tag Content
Uniprot ID A0A452G6R9
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000032255
Ensembl nucleotide ID ENSCHIG00000026297
Gene name Uncharacterized protein
Gene symbol NECTIN1
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MARMGLAGAA GRWWGLALGL TAFFLPGAHA QMVQVNDSMY GFIGTDVVLH CSFANPLPGV 60
KITQVTWQKA TNGSKQNVAI YNPAMGVSVL APYRERVEFL RPSFTDGTIR LSRLELEDEG 120
VYICEFATFP AGNRESQLNL TVMAKPTNWI EGTQAVLRAR KGQDEKVLVA TCTSANGKPP 180
SVVSWETRLK GEAEYQEIRN PNGTVTVISR YRLVPSREAH RQSLACIVNY HMDRFWESLT 240
LNVQYEPEVT IEGFDGNWYL QRMDVKLTCK ADANPPATEY HWTTLNGSLP KGVEAQNRTL 300
FFRGPINYSL AGTYICEATN PIGTRSGQVE VNITEFPYTP SPPEHGRRAG PVPTAIVGGV 360
VGSVLLVLIV VGGIVVALRR RRHTFKGDYS TKKHVYGNGY SKAGVPQHHP PMAQSLQYPE 420
DSDDDKKAGP LGGSSYEEEE EEEGGGGERK VGGPHPKYDE DAKRPYFTVD EAEARQDGYG 480
DRTLGYQYDP EQLDLAENMV SQNDGSFISK KE 512

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologNECTIN1489363F1PCB6Canis lupus familiarisPredictionMore>>
1:1 orthologNECTIN1A0A452G6R9Capra hircusPredictionMore>>
1:1 orthologNECTIN15818Q15223Homo sapiensPublicationMore>>
1:1 orthologNectin158235Q9JKF6E15.0Mus musculusPredictionMore>>
1:1 orthologNECTIN1H2Q4Y8Pan troglodytesPredictionMore>>
1:1 orthologNECTIN1F1S9T5Sus scrofaPredictionMore>>
1:1 orthologNectin1192183F1LNP8Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005911 cell-cell junction
GO:0016021 integral component of membrane
GO:0045202 synapse
GO:0050839 cell adhesion molecule binding
GO:0042803 protein homodimerization activity
GO:0007155 cell adhesion
GO:0051963 regulation of synapse assembly
GO:0019062 virion attachment to host cell

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0393 Immunoglobulin domain
KW-0472 Membrane
KW-1185 Reference proteome
KW-0677 Repeat
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR013162 CD80_C2-set
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR013106 Ig_V-set
IPR041849 Nectin-1_Ig1
IPR041850 Nectin-1_Ig2
IPR033314 Nectin1

PROSITE

PROSITE ID PROSITE Term
PS50835 IG_LIKE

Pfam

Pfam ID Pfam Term
PF08205 C2-set_2
PF07686 V-set