| Tag | Content |
|---|---|
| Uniprot ID | A0A452G8R3 |
| Entrez ID | 102170303 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018048629.1 |
| Ensembl protein ID | ENSCHIP00000032862 |
| Ensembl nucleotide ID | ENSCHIG00000026663 |
| Gene name | Tubby-like protein |
| Gene symbol | TULP3 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MESSLRRPGP RGDSAFEDET MKLRQLKLDN QRALLEKKQR KKRLEPLMVQ PNLEARPRRA 60 RPRGCEEHAL LVEPQAPHGG VVLQGVCSGS VPYCCRRALT DLGEGRAFSG IDGPAAFLKP 120 DAQDVDTRLH VLTVGSSATE DTEGSADGES AQDPASKPDL QEVLRKHGIS GSLNFDEEET 180 DGEEGEGNQL RSQSPCSEAE RPGSASSQKP APGTGASRTA SPHSDIQLGE MEDLEGFAYS 240 PAPRGVTVKC RITRDKKGMD RGLFPTYYMH LEKDEDRKIF LLAGRKRKKS KTSNYLISTD 300 PTDLSREGES YIGKLRSNLM GTKFTVYDHG VSPAKAQGLL EKAYMRQELA AVCYETNVLG 360 FKGPRKMSVI IPGMNMNHER IPFQPRNDHE SLLSKWQNKA MENLIELHNK SPVWNDDTQS 420 YVLNFHGRVT QASVKNFQIV HDNDPDYIIM QFGRVADDVF TLDYNYPLCA LQAFAIGLSS 480 FDSKLACE 488 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TULP3 | F1N7S0 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | TULP3 | 611832 | F1PNR7 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | TULP3 | 102170303 | A0A452G8R3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TULP3 | 7289 | O75386 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Tulp3 | 22158 | O88413 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | TULP3 | H2R7L6 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | 100511196 | A0A480JWW4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | TULP3 | 100341264 | G1SUQ3 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Tulp3 | F1M656 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0097731 | 9+0 non-motile cilium |
| GO:0005930 | axoneme |
| GO:0097546 | ciliary base |
| GO:0005730 | nucleolus |
| GO:0005654 | nucleoplasm |
| GO:0005886 | plasma membrane |
| GO:0019899 | enzyme binding |
| GO:0001664 | G protein-coupled receptor binding |
| GO:0120160 | intraciliary transport particle A binding |
| GO:0035091 | phosphatidylinositol binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0060348 | bone development |
| GO:0007420 | brain development |
| GO:0060434 | bronchus morphogenesis |
| GO:0021953 | central nervous system neuron differentiation |
| GO:0031076 | embryonic camera-type eye development |
| GO:0042733 | embryonic digit morphogenesis |
| GO:0048702 | embryonic neurocranium morphogenesis |
| GO:0061548 | ganglion development |
| GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning |
| GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning |
| GO:0001843 | neural tube closure |
| GO:0061512 | protein localization to cilium |
| GO:0008277 | regulation of G protein-coupled receptor signaling pathway |
| GO:0060831 | smoothened signaling pathway involved in dorsal/ventral neural tube patterning |