| Tag | Content |
|---|---|
| Uniprot ID | A0A5G2R540 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000072344 |
| Ensembl nucleotide ID | ENSSSCG00000001816 |
| Gene name | BLM RecQ like helicase |
| Gene symbol | BLM |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRETGIMAAI PQNNLQEQLE RHSARKLNNK LSLSKPKSSG FTFKKKAPSA KDLSITSVSV 60 AKTPVLSDKD VNVTEAFSFS EPLSHTTDQH KRINDFKNTP AGQQTKRVSS QQPLLPDLSQ 120 VPQEVLCTSQ NTPVIKESRD ATFKKLEFSS SSDSCITFND WDDMDDFDTS GNSKTFVTPL 180 RNNFVRVSTA QKSKKSKRNF LKSQFDKINT VKTDLIPPSS ESKQAYLTKK QKDDSEWLSS 240 DVICIDDDDP NSEEHINEDT QENRSLKTHL EEKRDNCEKE KSLEETELHS VEKSSCIELN 300 EDDYDIDYVP PSPEEGMTST SSSSLKCSSM LKDLDTSDRR DGLGTSEDLS EPEKMTSQQP 360 NPETSTNCEA GQINVQQQLI RVMDHICKLL DTIPDDKLKA LDCGNELLQQ RDMRRKLLAE 420 ADFNTCDASA LALLWRCRPA SLGSPVASVS SPSAFPNGNS CPTGNSVKEL AFPHCLSNSF 480 SSGEHLLTTT PGKTGFSATT KTVFERPPFN SHLQKSFVSS NWAETPRVEK RNESSYFPGN 540 VLTSTAVKDQ NKHTTSINDL EREIQASCDI DNFDIDDFDD DDDDWENMMH NLAASKSSTA 600 VYQPIKEGRP VKSVSERISS AKTDSLPVAS TAQNKNFSES IHNYTDKSEQ NLTSRNLKHK 660 HFQSLNFPHT KEMMKIFHKK FGLHNFRTNQ LEAINAALLG EDCFILMPTG GGKSLCYQLP 720 ACVSSGVTIV ISPLRSLIVD QVQKLTSLDI PATYLTGDKT DSEATSIYLQ LSKKDPIIKL 780 LYVTPEKVCA SNRLISTLEN LYNRKLLARF VIDEAHCVSQ WGHDFRPDYK RMNMLRQKFP 840 SVPVMALTAT ANPRVQKDIL TQLKILRPQV FTMSFNRHNL KYYVLPKKPK KVAFDCLEWI 900 RKHHPHDSGI IYCLSRRECD TMADTLQKDG LAALAYHAGL SDSARDEVQH KWINQDGCQV 960 ICATIAFGMG IDKPDVRFVI HASLPKSVEG YYQESGRAGR DGEISQCLLF YTYHDVTRLK 1020 RLILMEKDGN HHTKETHFNN LYSMVHYCEN IAECRRIQLL AYFGENEFNP NFCKKYPDVS 1080 CDNCCKTKDY KTRDVTDDVK NIVRFVQEHS SSRGARNIGS SGRFTMNMLV DIFLGSKSAK 1140 LQSGIFGKGS AYSRHNAERL FKKLILDKIL DEDLYINAND QPIAYIMLGD KAQAVLNGHL 1200 KVDFMETENS SSVKKQKALV AKVSQREEMV KKCLGELTEV CKSLGKVFGV HYFNIFNTTT 1260 LKKLAESLSS DPEVLLQIDG VTEDKLEKYG AEVIPILQKY SEWTVPAEDN SPRRSPSSCR 1320 GSGRNAPEEL DEETLISSHY FANKTKNERK RKRIPASQRS KRRKTSFSGS KAKG 1374 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BLM | 100685609 | E2RS76 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BLM | A0A452E3H5 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BLM | 641 | P54132 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Blm | 12144 | O88700 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BLM | A0A2I3SP55 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | BLM | A0A5G2R540 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | BLM | 100345123 | G1T6H2 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Blm | D3ZQW1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0043138 | 3'-5' DNA helicase activity |
| GO:0005524 | ATP binding |
| GO:0003677 | DNA binding |
| GO:0006310 | DNA recombination |
| GO:0006281 | DNA repair |
| GO:0006260 | DNA replication |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| InterPro ID | InterPro Term |
|---|---|
| IPR012532 | BDHCT |
| IPR032439 | BDHCT_assoc |
| IPR032437 | BLM_N |
| IPR011545 | DEAD/DEAH_box_helicase_dom |
| IPR002464 | DNA/RNA_helicase_DEAH_CS |
| IPR004589 | DNA_helicase_ATP-dep_RecQ |
| IPR014001 | Helicase_ATP-bd |
| IPR001650 | Helicase_C |
| IPR010997 | HRDC-like_sf |
| IPR002121 | HRDC_dom |
| IPR027417 | P-loop_NTPase |
| IPR032284 | RecQ_Zn-bd |
| IPR018982 | RQC_domain |
| IPR036388 | WH-like_DNA-bd_sf |
| IPR036390 | WH_DNA-bd_sf |