Gene: TGDS

Basic information

Tag Content
Uniprot ID A6QLW2
Entrez ID 534594
Genbank protein ID AAI48107.1
Genbank nucleotide ID NM_001101159.1
Ensembl protein ID
Ensembl nucleotide ID
Gene name dTDP-D-glucose 4,6-dehydratase
Gene symbol TGDS
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSVAGRAESL GPPDSFAKRV LVTGGAGFIA SHMIVSLVED YPNYMIINLD KLDYCASLKN 60
LETISNKQNY KFIQGDICDS HFVKLLFETE KIDIVLHFAA QTHVDLSFVR AFEFTYVNVY 120
GTHVLVSAAH EARVEKFIYV STDEVYGGSL DKEFDESSPK QPTNPYASSK AAAECFVQSY 180
WEQYKFPVVI TRSSNVYGPH QYPEKVIPKF ISLLQHNRKC CIHGTGLQTR NFLYATDVVE 240
AFLTVLKKGK PGEIYNIGTN FEMSVLQLAK ELIQLIKETN SESEMENWVD YVDDRPTNDM 300
RYPMKSEKIH GLGWRPKVPW KEGIKKTIEW YRENFHNWKN AEKALEPFPV QPPFV 355

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTGDS534594A6QLW2Bos taurusPredictionMore>>
1:1 orthologTGDS485521E2QWQ8Canis lupus familiarisPredictionMore>>
1:1 orthologTGDS102170331A0A452FWY8Capra hircusPredictionMore>>
1:1 orthologTGDS23483O95455Homo sapiensPredictionMore>>
1:1 orthologTgds76355Q8VDR7CPOMus musculusPublicationMore>>
1:1 orthologTGDS467299H2Q7P8Pan troglodytesPredictionMore>>
1:1 orthologTGDSF1RP60Sus scrofaPredictionMore>>
1:1 orthologTGDS100354182G1SYY5Oryctolagus cuniculusPredictionMore>>
1:1 orthologTgdsA0A0G2JZS4Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0008460 dTDP-glucose 4,6-dehydratase activity
GO:0009225 nucleotide-sugar metabolic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0456 Lyase
KW-0520 NAD
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR005888 dTDP_Gluc_deHydtase
IPR016040 NAD(P)-bd_dom
IPR036291 NAD(P)-bd_dom_sf

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF16363 GDP_Man_Dehyd