| Tag | Content |
|---|---|
| Uniprot ID | A8KC65; F1MM45; |
| Entrez ID | 510157 |
| Genbank protein ID | AAI54377.1 |
| Genbank nucleotide ID | NM_001206380.1 |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | SLC12A5 protein |
| Gene symbol | SLC12A5 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | VRVCVRRAGG HCSFFLRGAE SERARASERA AKAGRGARAR RRSHPRARRR AATMLNNLTD 60 CEDGDGGANP GDGNPKESSP FINSTDTEKG KEYDGKNMAL FEEEMDTSPM VSSLLSGLAN 120 YTNLPQGSRE HEEAENNEGG KKKPVQAPRM GTFMGVYLPC LQNIFGVILF LRLTWVVGIA 180 GIIEAFCMVF ICCSCTMLTA ISMSAIATNG VVPAGGSYYM ISRSLGPEFG GAVGLCFYLG 240 TTFAGAMYIL GTIEILLAYL FPAMAIFKAE DASGEAAAML NNMRVYGTCV LTCMATVVFV 300 GVKYVNKFAL VFLGCVILSI LAIYAGVIKS AFDPPNFPIC LLGNRTLSRH GFDVCAKLAW 360 EGNETVTTRL WGLFCSSRFL NATCDEYFMR NNVTEIQGIP GAASGLIKEN LWSSYLTKGV 420 IVERRGMPSA GLADGTPIDM DHPYVFSDMT SYFTLLVGIY FPSVTGIMAG SNRSGDLRDA 480 QKSIPTGTIL AIATTSAVYI SSVVLFGACI EGVVLRDKFG EAVNGNLVVG TLAWPSPWVI 540 VIGSFFSTCG AGLQSLTGAP RLLQAISRDG IVPFLQVFGH GKANGEPTWA LLLTACICEI 600 GILIASLDEV APILSMFFLM CYMFVNLACA VQTLLRTPNW RPRFRYYHWT LSFLGMSLCL 660 ALMFICSWYY ALVAMLIAGL IYKYIEYRGA EKEWGDGIRG LSLSAARYAL LRLEEGPPHT 720 KNWRPQLLVL VRVDQDQNVV HPQLLSLTSQ LKAGKGLTIV GSVLEGTFLD NHPQAQRAEE 780 SIRRLMEAEK VKGFCQVVIS SNLRDGVSHL IQSGGLGGLQ HNTVLVGWPR NWRQKEDHQT 840 WRNFIELVRE TTAGHLALLV TKNVSMFPGN PERFSEGSID VWWIVHDGGM LMLLPFLLRH 900 HKVWRKCKMR IFTVAQMDDN SIQMKKDLTT FLYHLRITAE VEVVEMHESD ISAYTYEKTL 960 VMEQRSQILK QMHLTKNERE REIQSITDES RGSIRRKNPA NTRLRLNVPE ETAGDSEEKP 1020 EEEVQLIHDQ SAPSCPSSSP SPGEEPEVEG EADPEKVHLT WTKDKSVAEK NKGPSPVSSE 1080 GIKDFFSMKP EWENLNQSNV RRMHTAVRLN EVIVKKSQDA KLVLLNMPGP PRNRNGDENY 1140 MEFLEVLTER LDRVMLVRGG GREVITIYS 1169 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SLC12A5 | 510157 | A8KC65 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SLC12A5 | A0A452EYG1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | SLC12A5 | 57468 | Q9H2X9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Slc12a5 | 57138 | Q91V14 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SLC12A5 | A0A2I3RM58 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | 100155991 | A0A4X1U3U5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Slc12a5 | F1LNP4 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005623 | cell |
| GO:0005887 | integral component of plasma membrane |
| GO:0045202 | synapse |
| GO:0015379 | potassium:chloride symporter activity |
| GO:0006884 | cell volume homeostasis |
| GO:0007268 | chemical synaptic transmission |
| GO:0055064 | chloride ion homeostasis |
| GO:1902476 | chloride transmembrane transport |
| GO:0055075 | potassium ion homeostasis |
| GO:1990573 | potassium ion import across plasma membrane |