Gene: satb2

Basic information

Tag Content
Uniprot ID A8WIP9
Entrez ID 563435
Genbank protein ID
Genbank nucleotide ID NM_001128532.1
Ensembl protein ID ENSDARP00000083309
Ensembl nucleotide ID ENSDARG00000061885
Gene name DNA-binding protein SATB
Gene symbol satb2
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MERGGGESPR LRDSPERRGS SSPDIGCPPQ KLGRLELNGS PTGHRSRHNG APQRPLSGLM 60
IPVFCVVEQM DGGMISDGES REEHAEFVLV RKDILFTQLV ETALLALGYS HSSAAQAHGI 120
IKVGRWNPLP IHYLTDAPEA TVADMLLDVY HMVTLRIQLQ SFAKLEDLPS EQWNHATVRN 180
ALKELLKEMN QSTLAKECPL SQSMISSIVN SSYYANVSTA KCQEFGRWYK KYKKIKGDYL 240
WQGREGSEIK VERDNIADFC VLAQRPPPHL TALGQLGPLN SAGSLVKGNS GEPQNSAQSQ 300
PPPQGQPQPP SSLGQLHHSP PLRAQVPPPP PPAALQPLLA PGGLLSPQLS PQLVRQQLAM 360
AHLINQQLAV SRLLHQHPQA LNQQFLNHPP IPRPSKSGGP GEPGSNPSAA EVSSDIYQLV 420
RDELKRASVS QAVFARVAFN RTQGLLSEIL RKEEDPRSAS QSLLVNLKAM QNFLNLPESE 480
RDRIYQEERE RSMNPPVSLP PSTNPSPGAV RLSQCKTPNP DLPVKLEPLV NITSAIYDEI 540
QQEMKRAKVS QALFAKVAAN KSQGWLCELL RWKESPSPEN RTLWENLCTI RRFLSLPQTD 600
RDMVYEEESR HHHSERLHTV LHLPTDPQAL HRQPMQPLKD HSPIREDPIP SSGAEENPQA 660
NTGSGNNGPV VSVTKKPRSR TKISLEALGI LQSFIQDVGL YPDQEAIHTL SAQLDLPKHT 720
IVKFFQNQRY HVKHHGRLKE LGSEGGGVDV AEYRDEELLS SSEDAESSED GHEEIYSGHE 780
SAPAGAANSV STPALSSVQD ENKDKCLPLG TVRPNSLPPC SSSSSPRDQA DYQR 834

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologSATB2102171018A0A452FN88Capra hircusPredictionMore>>
1:1 orthologSATB223314Q9UPW6Homo sapiensPublicationMore>>
1:1 orthologSatb2212712Q8VI24CPOE12.5, E14.25, E13.5, E14.5, E16.5Mus musculusPublicationMore>>
1:1 orthologSATB2459856A0A2I3SX19Pan troglodytesPredictionMore>>
1:1 orthologSATB2I3LRU7Sus scrofaPredictionMore>>
1:1 orthologSATB2100351405G1SXR2Oryctolagus cuniculusPredictionMore>>
1:1 orthologSatb2501145D3ZJ19Rattus norvegicusPredictionMore>>
1:1 orthologsatb2563435A8WIP9Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0006338 chromatin remodeling
GO:0055113 epiboly involved in gastrulation with mouth forming second
GO:0006357 regulation of transcription by RNA polymerase II

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome
KW-0804 Transcription
KW-0805 Transcription regulation

Interpro

InterPro ID InterPro Term
IPR003350 CUT_dom
IPR032355 CUTL
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
IPR039673 SATB1/SATB2
IPR038216 SATB_CUTL_sf
IPR038224 SATB_ULD_sf
IPR032392 ULD

PROSITE

PROSITE ID PROSITE Term
PS51042 CUT
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF02376 CUT
PF16557 CUTL
PF00046 Homeodomain
PF16534 ULD